New eye drops aim to lower glaucoma pressure

NCT ID NCT06441643

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tested two new eye drop formulas, AR-17043 and PG043, in 426 people with open-angle glaucoma or ocular hypertension. The goal was to see if they safely lower eye pressure better than existing drops. Participants received different doses of the study drops or standard treatments over several weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AR-17043 and PG043 (AR-17043/Latanoprost) eye drops

What this could lead to

If successful, this could lead to new eye drop options that lower eye pressure more effectively for people with glaucoma.

What could go wrong

This is an early phase 2 trial, so the results may not confirm safety or effectiveness. The drops may not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glaucoma ocular hypertension open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Coastal Research Associates

    Roswell, Georgia, 30076, United States

  • Eye Center of Northern Colorado, PC

    Fort Collins, Colorado, 80528, United States

  • Eye Research Foundation

    Newport Beach, California, 92663, United States

  • James D. Branch Ophthalmology

    Winston-Salem, North Carolina, 27101, United States

  • North Bay Eye Associates

    Petaluma, California, 94954, United States

  • Orange County Ophthalmology Medical Group

    Garden Grove, California, 92843, United States

  • Piedmont Eye Center

    Lynchburg, Virginia, 24502, United States

  • Rochester Ophthalmological Group

    Rochester, New York, 14618, United States

  • Scott & Christie and Associates, PC

    Cranberry Township, Pennsylvania, 16066, United States

  • Total Eye Care PA

    Memphis, Tennessee, 38119, United States

  • United Medical Research Institute

    Inglewood, California, 90301, United States

  • University Eye Specialists

    Maryville, Tennessee, 37803, United States