New eye drops aim to lower glaucoma pressure

NCT ID NCT06441643

Completed Disease control Sponsor: Alcon Research Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tested two new eye drop formulas, AR-17043 and PG043, in 426 people with open-angle glaucoma or ocular hypertension. The goal was to see if they safely lower eye pressure better than existing drops. Participants received different doses of the study drops or standard treatments over several weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AR-17043 and PG043 (AR-17043/Latanoprost) eye drops
What this could lead to: If successful, this could lead to new eye drop options that lower eye pressure more effectively for people with glaucoma.
What could go wrong: This is an early phase 2 trial, so the results may not confirm safety or effectiveness. The drops may not work better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glaucoma ocular hypertension open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OCULAR HYPERTENSION OPEN-ANGLE GLAUCOMA

Contacts and locations

Locations

Coastal Research Associates

Roswell, Georgia, 30076, United States
Eye Center of Northern Colorado, PC

Fort Collins, Colorado, 80528, United States
Eye Research Foundation

Newport Beach, California, 92663, United States
James D. Branch Ophthalmology

Winston-Salem, North Carolina, 27101, United States
North Bay Eye Associates

Petaluma, California, 94954, United States
Orange County Ophthalmology Medical Group

Garden Grove, California, 92843, United States
Piedmont Eye Center

Lynchburg, Virginia, 24502, United States
Rochester Ophthalmological Group

Rochester, New York, 14618, United States
Scott & Christie and Associates, PC

Cranberry Township, Pennsylvania, 16066, United States
Total Eye Care PA

Memphis, Tennessee, 38119, United States
United Medical Research Institute

Inglewood, California, 90301, United States
University Eye Specialists

Maryville, Tennessee, 37803, United States

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