NON CYSTIC FIBROSIS BRONCHIECTASIS

This study tests an inhaled drug called ensifentrine in people with non-cystic fibrosis bronchiectasis, a lung condition that causes repeated infections and breathing trouble. About 284 adults will receive either the drug or a placebo twice daily for at least 24 weeks. The main g…

This study tests a device called SIMEOX that uses gentle air pulses to help clear mucus from the lungs of people with bronchiectasis (a chronic lung disease). Participants use the device at home along with remote physiotherapy sessions. The goal is to see if this approach improve…

This study tests an inhaled medicine called CSL787 in adults with non-cystic fibrosis bronchiectasis, a lung condition that causes frequent infections and breathing problems. The goal is to see if CSL787 can delay the next serious lung flare-up and reduce how often they happen. A…

This study tests an inhaled drug called GDC-6988 in people with lung diseases that cause thick mucus, like chronic bronchitis and non-CF bronchiectasis. The main goal is to check if the drug is safe and does not harm lung function. About 128 adults with stable disease will take t…

This study tests whether a home-based, digitally guided breathing and respiratory muscle training program, supported by a health coach, can improve exercise ability and lung function in people with non-cystic fibrosis bronchiectasis. Researchers will enroll 50 adults with this ch…

This study looks at a chronic lung disease called non-cystic fibrosis bronchiectasis, which causes persistent cough and infections. Researchers will study 320 patients and healthy volunteers in China to find biological markers and disease patterns. The goal is to better understan…

This is a very early-stage study to check the safety of a new oral drug called RSS0343 and see how the body processes it. The study will involve 48 healthy volunteers who will take the drug or a placebo for several days. Researchers will closely monitor for side effects and measu…