New home device aims to ease breathing and cut infections in lung disease
NCT ID NCT06487273
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study tests whether a device called SIMEOX, used at home with remote physiotherapy, can improve quality of life and reduce lung infections in people with bronchiectasis (a chronic lung disease with mucus buildup). About 622 adults will use the device daily or get standard care. The goal is to see if this approach helps clear mucus better and lowers the number of serious flare-ups over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SIMEOX airway clearance device and remote physiotherapy
- What this could lead to
- If it works, this could offer a convenient home-based treatment to improve daily life and reduce serious lung infections for people with bronchiectasis.
- What could go wrong
- This is a mid-stage trial with 622 participants, so results are not yet proven. The device may not work for everyone, and daily use could be burdensome.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CFR Dieulefit
RECRUITINGDieulefit, France
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CH Abbeville
RECRUITINGAbbeville, France
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CH Aix en Provence
RECRUITINGAix-en-Provence, France
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CH Albi
RECRUITINGAlbi, France
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CH Alpes-Léman
RECRUITINGContamine-sur-Arve, 74130, France
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CH Annecy
RECRUITINGAnnecy, France
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CH Bretagne Atlantique
RECRUITINGVannes, France
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CH Compiègne-Noyon
RECRUITINGCompiègne, 60200, France
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CH Cotentin
RECRUITINGCherbourg, France
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CH Le Puy-en-Velay
RECRUITINGLe Puy-en-Velay, 43000, France
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CH Libourne
RECRUITINGLibourne, 33500, France
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CH Pau
RECRUITINGPau, 64000, France
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CH Perpignan
NOT_YET_RECRUITINGPerpignan, France
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CH St Quentin
RECRUITINGSaint-Quentin, France
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CH Tarbes Lourdes
RECRUITINGTarbes, France
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CH Troyes
RECRUITINGTroyes, France
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CHI Créteil
RECRUITINGCréteil, 94000, France
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CHRU Brest
RECRUITINGBrest, 29200, France
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CHU Amiens Picardie
RECRUITINGAmiens, France
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CHU Angers
RECRUITINGAngers, 49033, France
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CHU Grenoble-Alpes
RECRUITINGGrenoble, 38043, France
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CHU La Réunion Félix Guyon
RECRUITINGSaint-Denis, Reunion
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CHU La Réunion Sud
RECRUITINGSaint-Pierre, Reunion
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CHU Limoges
RECRUITINGLimoges, France
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CHU Nice
RECRUITINGNice, 06002, France
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CHU Nîmes
RECRUITINGNîmes, 30900, France
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CHU Poitiers
RECRUITINGPoitiers, 86021, France
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CHU Reims
RECRUITINGReims, 51092, France
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CHU Rennes
RECRUITINGRennes, 35033, France
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CHU Rouen
WITHDRAWNRouen, France
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CHU Toulouse
RECRUITINGToulouse, France
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Centro Clínico Académico de Braga (2CA-Braga) ULS de Braga
NOT_YET_RECRUITINGBraga, 4710-243, Portugal
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clinique Aressy
RECRUITINGAressy, 64320, France
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Clinique Victor Pauchet
RECRUITINGAmiens, 80090, France
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Fondation Ildys
RECRUITINGRoscoff, 29684, France
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Groupe Hospitalier La Rochelle - Ré-Aunis
SUSPENDEDLa Rochelle, France
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Groupe Hospitalier du Havre
WITHDRAWNMontivilliers, France
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HCL - centre de Hyères
RECRUITINGHyères, France
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HCL- Hôpital Croix-Rousse
RECRUITINGLyon, 69004, France
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Heartland Hospital, University Hospitals Birmingham, NHS Foundation Trust
NOT_YET_RECRUITINGBirmingham, B9 5SS, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Senhora de Oliveira Guimarães ULS Alto Ave
NOT_YET_RECRUITINGCreixomil, 4835-044, Portugal
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Bicêtre (AP-HP)
WITHDRAWNLe Kremlin-Bicêtre, 94270, France
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Hôpital Cochin (AP-HP)
RECRUITINGParis, 75014, France
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Hôpital Européen de Marseille
RECRUITINGMarseille, France
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Hôpital Foch
RECRUITINGSuresnes, France
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Instituto CUF
NOT_YET_RECRUITINGPorto, 4460-188, Portugal
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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LMU Klinikum
RECRUITINGMünchen, 80336, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medizinische Klinik V University hospital
RECRUITINGAachen, 52074, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Montpellier Hospital Center
RECRUITINGMontpellier, 34090, France
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NHS Lothian
RECRUITINGEdinburgh, EH3 9DN, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Victoria Hospital, Belfast Health and Social Care Trust
RECRUITINGBelfast, BT12 6BA, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Szpital Uniwersytecki w Krakowie
NOT_YET_RECRUITINGKrakow, 30-688, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Newcastle upon Tyne Hospitals NHS Foundation Trust
RECRUITINGNewcastle upon Tyne, NE7 7DN, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsklinikum Schleswig-Holstein
NOT_YET_RECRUITINGLübeck, 23538, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Uniwersytecki Szpital Kliniczny w Poznaniu
NOT_YET_RECRUITINGPoznan, 60-355, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Uniwersytet Medyczny w Łodzi Nr 1 im. Norberta Barlickiego
RECRUITINGLodz, 90-153, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wythenshawe Hospital, Manchester University, NHS Foundation Trust
NOT_YET_RECRUITINGManchester, M23 9LT, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A vibrating vest may help children with damaged lungs breathe easier
- Can a new biologic drug delay dangerous lung Flare-Ups?
- Inhaled experimental drug targets tough lung infections
- New drug trial aims to tame chronic lung infections
- Scientists develop risk score to forecast bronchiectasis attacks
- 500 patients to test if daily azithromycin keeps bronchiectasis attacks at bay