NEUROLOGIC DISORDER

This study tests a brain-computer implant (Stentrode) for people with paralysis from motor neuron disease or similar conditions. The device is placed in a blood vessel near the brain and aims to let users control computers or assistive devices with thought. The trial focuses on s…

This study tests a brain-computer implant (BCI) that lets people with ALS or motor neuron disease control digital devices using only their thoughts. Ten participants will receive the implant, and researchers will monitor safety and how well the device works over one year. The goa…

This study tests whether a soft robotic glove called Carbonhand can help people with hand weakness from injury or nerve conditions perform daily activities at home. Five participants will use the glove for six weeks while researchers measure arm activity, grip strength, and well-…

This study compares mirror therapy, brain stimulation (rTMS), and robotic hand training added to standard rehab for stroke patients. 120 adults who had a stroke at least 3 months ago will receive 20 sessions over 4 weeks. The goal is to see which approach best improves arm functi…

This pilot study tests a communication tool for parents of children with severe neurological problems in the intensive care unit. Parents pick 1-3 photos that show what matters to their family and share them with doctors. The goal is to see if this approach is practical, acceptab…

This study is testing whether listening to favorite music for 30 minutes a day can improve consciousness in people with severe brain injuries, such as traumatic brain injury or disorders of consciousness. Sixty-six patients in early neurological rehabilitation will be randomly as…

This study is testing a full-body suit that delivers mild electrical pulses to muscles. The goal is to see if it safely reduces spasticity, overactive reflexes, and pain in people with neurological conditions like multiple sclerosis or fibromyalgia. Fifteen adults will try both t…

This study creates a large registry of people with Rett syndrome, a rare genetic disorder that causes severe intellectual and physical disabilities. Researchers will collect information from doctors and caregivers to understand how the disease progresses over time. The goal is to…

This study tests whether advanced MRI scans that map the brain's structural and functional connections can better predict neurological recovery in coma patients after cardiac arrest than standard methods. Researchers will scan 263 adults who remain unconscious at least 72 hours a…

This study looks at whether low magnesium in the blood is linked to memory, attention, and other thinking problems after a stroke. Researchers will measure magnesium levels and give cognitive tests to 80 stroke patients over several weeks. The goal is to understand if magnesium d…

This study looks at whether the position a person is in during a urodynamic exam (a test that measures bladder function) affects the diagnosis of an overactive bladder in people with multiple sclerosis or Parkinson's disease. Researchers will compare results from tests done while…

This study is creating a shared database of children who have received deep brain stimulation (DBS) for movement disorders like dystonia, epilepsy, or Tourette syndrome. By pooling data from multiple hospitals, researchers hope to answer key questions about who benefits most and …

This study collects information from 500 children worldwide who have both epilepsy and movement disorders caused by specific gene changes. Researchers will analyze medical records to find patterns linking symptoms to genetics. The goal is to create a shared database that helps do…

This study is collecting information from 200 people with cerebral palsy, multiple sclerosis, stroke, fibromyalgia, or similar nerve disorders to see how the EXOPULSE Suit affects their balance and risk of falling over time. Participants will be followed routinely, and researcher…

This study is creating a huge collection of medical images and health information from 50,000 adults. Researchers will use advanced CT and MRI scans to find hidden patterns that could help predict, diagnose, and treat diseases like cancer, heart disease, and brain disorders. Part…

This study reviews medical records of 200 children with obstructive sleep apnea who had tonsil surgery. Researchers want to find out how often breathing problems happen after surgery, especially in children with obesity, Down syndrome, or other health issues. The goal is to bette…

This study follows 130 patients with disorders of consciousness after stroke, traumatic brain injury, or oxygen deprivation. Researchers will use brain scans, electrical tests, and regular check-ups to find factors that might predict if and when patients regain consciousness. The…

This study examines whether memory problems after a type of brain bleed (aneurysmal subarachnoid hemorrhage) are linked to a smaller hippocampus, a brain area key for memory. Researchers will compare 30 patients in rehabilitation with healthy volunteers using memory tests and MRI…