NEURODEGENERATIVE DISEASES
Clinical trials for NEURODEGENERATIVE DISEASES explained in plain language.
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Could a natural hormone rebuild brains in Alzheimer's?
Disease control OngoingThis phase 2 trial tests whether allopregnanolone, a natural hormone, can safely help repair the brain in people with early Alzheimer's disease. About 100 volunteers aged 55 to 80 will receive weekly infusions of the drug or a placebo for several months. Researchers will measure …
Matched conditions: NEURODEGENERATIVE DISEASES
Phase: PHASE2 • Sponsor: University of Arizona • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New dosing strategy aims to make Alzheimer's drug safer and more effective
Disease control OngoingThis study tests different dosing schedules of the drug donanemab in about 1,175 people with early symptomatic Alzheimer's disease. The goal is to find a regimen that lowers brain amyloid plaques while reducing the risk of a side effect called ARIA-E (brain swelling or small blee…
Matched conditions: NEURODEGENERATIVE DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a new drug slow Alzheimer's? large trial underway
Disease control OngoingThis phase 3 study tests whether donanemab, an antibody given through an IV, can safely slow cognitive decline in 1500 people with early Alzheimer's. Participants receive either the drug or a placebo for up to 93 weeks. The main goal is to measure changes in thinking and daily fu…
Matched conditions: NEURODEGENERATIVE DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New tool aims to protect rights of those with memory loss
Knowledge-focused OngoingThis study is creating a simple test to check if people with Alzheimer's or similar conditions can understand and agree to medical decisions. Researchers will work with 100-150 participants to compare the new test with existing methods and look at brain scans and blood markers. T…
Matched conditions: NEURODEGENERATIVE DISEASES
Sponsor: Ludwig-Maximilians - University of Munich • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Massive brain chart project aims to spot Alzheimer's and MS earlier
Knowledge-focused ENROLLING_BY_INVITATIONThis study will collect brain scans from over 10,000 healthy people in China to create standard brain charts. These charts will show what a normal brain looks like at different ages. Doctors can then compare a patient's brain scan to these charts to help diagnose diseases like mu…
Matched conditions: NEURODEGENERATIVE DISEASES
Sponsor: Beijing Tiantan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New headset lets ALS patients type with their brain
Knowledge-focused OngoingThis study is testing a new, comfortable headset that reads brain signals to help people with ALS type on a virtual keyboard. The goal is to improve the device so it can be used in daily life. Five people with ALS will try the headset, and researchers will measure how easy it is …
Matched conditions: NEURODEGENERATIVE DISEASES
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC