NEOADJUVANT THERAPY

This study aims to see if a new drug combination can help shrink pancreatic tumors before surgery. It will test an immunotherapy drug (adebrelimab) plus two standard chemotherapy drugs in about 30 patients. The goal is to see if this approach makes surgery more successful and imp…

This study is testing whether adding two new drugs (zanidatamab and tislelizumab) to standard chemotherapy or radiation works better for people with HER2-positive stomach or colorectal cancers. It will involve about 70 adults with specific types of advanced or spreading cancer. T…

This study is testing a new two-in-one immunotherapy drug called QL1706, given with chemotherapy before surgery for early triple-negative breast cancer. The goal is to shrink tumors and see if some patients can safely skip a type of chemotherapy that can harm the heart long-term.…

This study is testing whether a drug called Vebreltinib can shrink tumors in patients with a specific genetic type of non-small cell lung cancer before they have surgery. About 30 eligible patients will take the drug for 8 weeks prior to their planned operation. The main goal is …

This study is testing if some patients with a common type of early breast cancer can avoid chemotherapy before surgery. Instead, they would receive a targeted pill (abemaciclib) plus hormone therapy. The goal is to see if this gentler approach works as well for shrinking tumors, …

This study is testing whether a new drug called Ivonescimab (AK112), when given with standard chemotherapy before surgery, can help people with a type of esophageal cancer. The goal is to shrink the tumor and kill any hidden cancer cells to improve the chance of a successful surg…

This study tests whether combining two drugs (SKB264 and pembrolizumab) given before surgery can eliminate cancer cells in patients with stage II-III triple-negative breast cancer. The trial will enroll 52 patients who haven't had previous cancer treatment to see if this combinat…

This study tests whether a family-supervised program of exercise, nutrition, and psychological support during chemotherapy before stomach cancer surgery can help patients recover better. The program aims to reduce serious complications after surgery and improve recovery. Research…

This study is testing if wearing a tight surgical glove on one hand during chemotherapy can prevent or reduce nerve damage, a common and painful side effect. It will involve 44 adults with breast cancer who are receiving a specific type of chemo. The goal is to see if this simple…

This study aims to find blood markers that might predict how well breast cancer patients respond to chemotherapy before surgery. Researchers will collect blood samples from 80 patients before and after their standard chemotherapy treatment. They'll look for tiny molecules in the …

This study aims to develop an artificial intelligence (AI) tool to help doctors choose the best treatment for people with esophageal cancer. It will analyze thousands of patient scans and tissue samples to learn which treatments lead to the best outcomes. The goal is to create a …