NEOADJUVANT THERAPY

This study tested a combination of two drugs (cadonilimab and lenvatinib) given before surgery to 39 people with kidney cancer that was difficult to operate on while saving the kidney. The goal was to shrink the tumor enough to allow a partial, kidney-sparing surgery instead of r…

This phase 2 trial tested the drug serplulimab (an immunotherapy) combined with standard chemotherapy in 30 people with stage II-IIIA non-small cell lung cancer that could be surgically removed. The treatment was given before and after surgery to see if it could shrink tumors and…

This study developed an AI model to predict how well bladder cancer responds to treatment before surgery. Researchers used data from 469 patients, including medical images and genetic information, to train the AI. The goal is to help doctors choose the best treatment plan for eac…

This study followed 67 women with breast cancer to see how chemotherapy given before surgery (neoadjuvant chemotherapy) affects their physical abilities. Researchers measured muscle strength, balance, and fatigue before and after treatment. The goal was to better understand the p…

This study looked at 300 people with pancreatic cancer to see if changes in a specific type of tumor cell in the blood (called mesenchymal circulating tumor cells) could predict how well they respond to treatment and how long they live. Researchers tracked these cells over time i…