MUSCLE SPASTICITY
Clinical trials for MUSCLE SPASTICITY explained in plain language.
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New muscle relaxant drug MTR-601 tested in humans for first time
Symptom relief CompletedThis early-stage trial tested a new oral drug called MTR-601 in 89 healthy adults to see if it is safe and how the body processes it. The drug aims to reduce muscle stiffness and spasms, which could help people with conditions like cerebral palsy, multiple sclerosis, or stroke. S…
Matched conditions: MUSCLE SPASTICITY
Phase: PHASE1 • Sponsor: Motric Bio • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Light therapy shows promise for stiff muscles in kids with cerebral palsy
Symptom relief CompletedThis study tested whether shining a special light (photobiomodulation) on the calf muscles can reduce spasticity in children with cerebral palsy. Twelve children aged 2 to 18 received either real or placebo light therapy once a week for two months, alongside their usual care. The…
Matched conditions: MUSCLE SPASTICITY
Phase: PHASE2, PHASE3 • Sponsor: University of Nove de Julho • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New device aims to loosen stiff legs in stroke survivors
Symptom relief CompletedThis study tested a device called MyoRegulator® to see if it can reduce muscle stiffness (spasticity) in the lower leg after a stroke. 44 adults who had a stroke at least 6 months earlier took part. Half received real treatment and half received a sham (fake) treatment for 5 days…
Matched conditions: MUSCLE SPASTICITY
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Robot or human? new study compares arm therapy methods for stroke patients
Symptom relief CompletedThis study tested whether robot-assisted arm therapy works as well as traditional therapy with a physiotherapist for people recovering from a stroke. 58 adults who had a stroke within the past 6 weeks took part in a 6-week program doing the same arm exercises, either with a robot…
Matched conditions: MUSCLE SPASTICITY
Phase: NA • Sponsor: Wroclaw University of Health and Sport Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Which drug helps stroke recovery more? botox vs baclofen showdown
Symptom relief CompletedThis study tested two treatments for muscle stiffness (spasticity) that often occurs after a stroke. 184 people who had a stroke within the past two months received either botulinum toxin injections, oral baclofen, or a placebo. The goal was to see which treatment better helps mo…
Matched conditions: MUSCLE SPASTICITY
Phase: PHASE4 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Drug plus movement therapy may boost hand function in chronic stroke
Symptom relief CompletedThis study tested a new rehab method for people who had a stroke at least 6 months ago and still have hand weakness and stiffness. The approach combined a drug called cyproheptadine with active movement practice to help improve voluntary muscle control and strength. 96 participan…
Matched conditions: MUSCLE SPASTICITY
Phase: NA • Sponsor: Shirley Ryan AbilityLab • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC