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Which drug helps stroke recovery more? botox vs baclofen showdown

NCT ID NCT02462317

Completed Symptom relief Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two treatments for muscle stiffness (spasticity) that often occurs after a stroke. 184 people who had a stroke within the past two months received either botulinum toxin injections, oral baclofen, or a placebo. The goal was to see which treatment better helps motor recovery and reduces disability during the early recovery phase.

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Conditions

The condition(s) this trial relates to.

Muscle Spasticity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MUSCLE SPASTICITY

Contacts and locations

Locations

  • CHRU de Brest

    Brest, 29609, France

  • CHU Gui de Chauliac

    Montpellier, 34295, France

  • CHU Jean Minjoz

    Besançon, 25030, France

  • Centre Bouffard- Vercelli

    Cervera de la Marenda, 66290, France

  • Centre de rééducation MARIENIA

    Cambo-les-Bains, 64250, France

  • GH Lariboisière F.Widal

    Paris, 75013, France

  • Groupe Hospitalier Pitié-Salpêtrière

    Paris, 75013, France

  • Groupe Pellegrin, University Hospital Bordeaux

    Bordeaux, 33076, France

  • Hopital Rothschild

    Paris, 75012, France

  • Hôpital J Rebeyrol

    Limoges, 87042, France

  • Hôpital R. Poincarré

    Garches, 92380, France

  • Hôpital Swynghedauw

    Lille, 59000, France

  • Pôle MPR St Hélier

    Rennes, 35000, France

  • University Hospital Carémeau

    Nîmes, 30029, France

  • University Hospital Dijon

    Dijon, 21079, France

  • University Hospital Grenoble

    Échirolles, 38434, France

  • University Hospital, Toulouse

    Toulouse, Haute-Garonne, 31059, France

  • Université Reims Champagne Ardenne

    Reims, 51092, France

  • l'Institut Hélio Marin de la côte d'azur

    Hyères, 67082, France

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