MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Clinical trials for MILD AUTONOMOUS CORTISOL SECRETION (MACS) explained in plain language.
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Head-to-Head drug battle for a hidden hormone disorder
Disease control Recruiting nowThis study is comparing two existing drugs, metyrapone and osilodrostat, to see which one works better for adults with a condition where their adrenal glands produce too much cortisol. The goal is to control the hormone levels and improve related health problems like high blood p…
Matched conditions: MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Phase: PHASE4 • Sponsor: Laikο General Hospital, Athens • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Drug trial aims to tame silent hormone problem linked to heart and bone risks
Disease control Recruiting nowThis study is testing if a drug called Isturisa (osilodrostat) can help people with a condition where a small adrenal tumor causes mildly high cortisol levels long-term. Researchers want to see if taking the drug for two years improves related health issues like blood sugar, weig…
Matched conditions: MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Surgery or a shot? new study tests best fix for hidden hormone problem
Disease control Recruiting nowThis study is comparing two treatments for a condition where a small adrenal gland tumor causes mildly high cortisol levels. Researchers want to see if surgically removing the gland or using a weight-management medication (semaglutide) works better to improve the body's response …
Matched conditions: MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Hidden hormone danger: study hunts for best test to spot silent adrenal problem
Knowledge-focused Recruiting nowThis study aims to find the best combination of tests to detect a condition where small adrenal tumors produce slightly too much cortisol, a stress hormone. Researchers will follow 20 adults with these incidental tumors for four years to see if their health changes. The goal is t…
Matched conditions: MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC