MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Clinical trials for MILD AUTONOMOUS CORTISOL SECRETION (MACS) explained in plain language.
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Can a diabetes drug fix lingering health issues after adrenal surgery?
Disease control Not yet recruitingThis study tests whether the drug tirzepatide can improve blood pressure, weight, and blood sugar in people who still have metabolic problems after surgery to remove an adrenal gland. The condition, mild autonomous cortisol secretion (MACS), causes high blood pressure, diabetes, …
Matched conditions: MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Phase: PHASE2 • Sponsor: Alaa Sada • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could a drug tame excess cortisol in a common hormone disorder?
Disease control Not yet recruitingThis study tests whether the drug metyrapone can safely lower cortisol levels in people with mild autonomous cortisol secretion (MACS), a condition where the adrenal glands produce too much cortisol. Participants will receive either metyrapone or a placebo for a short period, and…
Matched conditions: MILD AUTONOMOUS CORTISOL SECRETION (MACS)
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC