METASTATIC NON-SMALL CELL LUNG CANCER
Clinical trials for METASTATIC NON-SMALL CELL LUNG CANCER explained in plain language.
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First test of new drug combo for advanced lung cancer
Disease control CompletedThis early-stage study tested whether combining two targeted cancer drugs (dacomitinib and osimertinib) is safe for people with advanced lung cancer that has spread and has a specific genetic change (EGFR mutation). The trial involved 22 patients who hadn't previously received th…
Matched conditions: METASTATIC NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Blood test guides precision strikes against lingering lung cancer
Disease control CompletedThis study tested a new strategy for controlling advanced lung cancer that has spread. It aimed to see if using a sensitive blood test to detect tiny amounts of leftover cancer could guide doctors to use targeted radiation or surgery on the remaining tumors. The goal was to see i…
Matched conditions: METASTATIC NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New drug duo targets lung cancer in the brain after other treatments fail
Disease control CompletedThis study tested whether two drugs, amivantamab and lazertinib, could help control advanced lung cancer that has an EGFR mutation and has spread to the brain or spinal fluid. It was for patients whose cancer had gotten worse or spread to the central nervous system despite previo…
Matched conditions: METASTATIC NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New drug combo tested in major lung cancer fight
Disease control CompletedThis large, completed Phase 3 trial tested if adding a new drug (vibostolimab) to a standard immunotherapy (pembrolizumab) and chemotherapy works better than the standard treatment alone for people newly diagnosed with advanced non-small cell lung cancer that has spread. The main…
Matched conditions: METASTATIC NON-SMALL CELL LUNG CANCER
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Muscle loss may predict cancer treatment success
Knowledge-focused CompletedThis study looked back at medical records to see if muscle loss and inflammation levels can help predict how well lung cancer patients respond to immunotherapy. Researchers analyzed data from 115 adults with advanced lung cancer who received immunotherapy treatment. They measured…
Matched conditions: METASTATIC NON-SMALL CELL LUNG CANCER
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Blood test could give early warning if lung cancer treatment is working
Knowledge-focused CompletedThis study tested whether changes in a blood test called ctDNA could predict how well treatment works for metastatic lung cancer. Researchers followed 100 patients to see if blood test results at 3 weeks matched later scan results. The goal was to find a faster way to know if a t…
Matched conditions: METASTATIC NON-SMALL CELL LUNG CANCER
Phase: NA • Sponsor: Centre Hospitalier Departemental Vendee • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:53 UTC