METASTATIC MALIGNANT SOLID NEOPLASM
Clinical trials for METASTATIC MALIGNANT SOLID NEOPLASM explained in plain language.
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Scientists test new drug duo in fight against tough cancers
Disease control CompletedThis early-stage study aimed to find the safest dose of two drugs, sapanisertib and ziv-aflibercept, when given together to patients with advanced solid tumors that had stopped responding to standard treatments. The main goal was to understand the side effects and determine the h…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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Scientists combine radiation with Immune-Boosting drugs to fight spreading cancers
Disease control CompletedThis study tested whether combining targeted radiation with immune-boosting drugs could help control advanced cancers that had spread to the lungs or liver. Researchers worked with 51 patients to find safe doses and see if this approach could shrink tumors both where radiation wa…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Magic mushroom therapy gets second shot at easing cancer anxiety
Symptom relief CompletedThis small, early-stage study tested whether a second round of psilocybin-assisted group therapy is safe and helpful for people with advanced cancer who still have significant anxiety after a first session. Fifteen participants with metastatic cancer received psilocybin in a cont…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Magic mushroom therapy tested to soothe cancer Patients' fears
Symptom relief CompletedThis study tested whether a pharmaceutical-grade form of psilocybin, the active compound in 'magic mushrooms,' given alongside group and individual therapy, is safe and helpful for reducing anxiety and depression in people with advanced, incurable cancer. It involved 55 adult par…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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New website aims to ease the burden of End-of-Life planning for cancer patients
Symptom relief CompletedThis study tested a special website designed to help people with advanced cancer plan for the end of their lives. It guided 100 participants through important tasks like making medical wishes, legal plans, and sharing their legacy. Researchers compared the website's effectiveness…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Mar 11, 2026 14:53 UTC
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Coaching helps latino cancer patients plan for difficult medical conversations
Knowledge-focused CompletedThis study tested whether a coaching program helps Latino cancer patients better understand and prepare for advance care planning—discussing the medical care they would want if they became too sick to speak for themselves. Researchers worked with 27 Latino patients who had advanc…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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A phase II study of oral infigratinib in adult patients with advanced or metastatic solid tumors with FGFR1-3 gene fusions or other FGFR genetic alterations
CompletedThis phase II trial studies how well infigratinib works in treating solid tumors that have spread to other places in the body (advanced or metastatic) in patients with FGFR gene mutations such as FGFR1-3 gene fusions or other FGFR genetic alterations. Mutations are any changes in…
Matched conditions: METASTATIC MALIGNANT SOLID NEOPLASM
Phase: PHASE2 • Sponsor: Sameek Roychowdhury
Last updated Mar 03, 2026 14:07 UTC