MANTLE CELL LYMPHOMA
Clinical trials for MANTLE CELL LYMPHOMA explained in plain language.
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New hope for frail elderly patients with rare blood cancer
Disease control Not yet recruitingThis study is testing whether a daily oral medication called pirtobrutinib can help control mantle cell lymphoma in older adults who are too frail for standard chemotherapy. It will enroll 56 previously untreated patients aged 70+ who are considered unfit or frail. Participants w…
Matched conditions: MANTLE CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Trial tests smart treatment switch for tough blood cancer
Disease control Not yet recruitingThis study is testing a new, personalized first treatment for older adults with mantle cell lymphoma, a type of blood cancer. It combines chemotherapy and targeted drugs, then adjusts the plan after four cycles based on how well the cancer is responding. The goal is to better con…
Matched conditions: MANTLE CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New immune cell attack tested for tough blood cancers
Disease control Not yet recruitingThis early-stage study is testing the safety of a new combination treatment for people with B-cell non-Hodgkin lymphoma that has come back or not responded to at least two prior therapies. The treatment adds an experimental therapy—'natural killer' (NK) immune cells from a donor—…
Matched conditions: MANTLE CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Paolo Caimi, MD • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Double-Drug boost aims to make Cancer-Killing cell therapy work better
Disease control Not yet recruitingThis study is testing whether adding two oral medications, sonrotoclax and zanubrutinib, to a standard cell therapy (CAR-T) can improve outcomes for adults with mantle cell lymphoma that has returned or stopped responding to prior treatment. The goal is to see if this drug combin…
Matched conditions: MANTLE CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Canadian Cancer Trials Group • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New hope offered when CAR-T fails: experimental drug targets tough lymphoma cases
Disease control Not yet recruitingThis study tests an experimental drug called glofitamab for people with mantle cell lymphoma whose cancer didn't respond well enough or came back after CAR-T cell therapy. About 41 participants will receive the drug to see if it can shrink their cancer and how safe it is. The goa…
Matched conditions: MANTLE CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Three-Drug attack on rare blood cancer: custom treatment based on risk
Disease control Not yet recruitingThis study is testing a combination of three medications (obinutuzumab, zanubrutinib, and lenalidomide) as the first treatment for adults with mantle cell lymphoma, a rare blood cancer. All 37 participants will receive the initial drug combination, then maintenance therapy tailor…
Matched conditions: MANTLE CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Mar 09, 2026 14:22 UTC