MALIGNANT MELANOMA

This is the first study in people testing a new drug called CTX-8371 for several advanced cancers that have stopped responding to standard treatments. Researchers will give increasing doses to a small group of patients to check if the drug is safe and what side effects it causes.…

This study is testing whether adding a new personalized cancer vaccine (V940) to standard immunotherapy (pembrolizumab) works better for advanced melanoma that has spread. The goal is to see if this combination helps patients live longer without their cancer getting worse compare…

This is the first human study of an experimental antibody drug called CBA-1205 for people with advanced solid tumors that haven't responded to standard treatments. The trial will test the drug's safety and find the right dose in 66 adults and children with various cancers includi…

This study is testing a new vaccine for people with melanoma who are at high risk of their cancer returning after surgery. The vaccine is made from specially modified melanoma cells designed to teach the patient's own immune system to recognize and attack any remaining cancer cel…

This early-stage trial is testing a new drug called AMT-253 for people with advanced melanoma or other solid tumors that have spread and cannot be removed by surgery. The study aims to find a safe dose and see if the drug can shrink tumors in patients who have already tried stand…

This study is testing a new drug, TCC1727, combined with other cancer medications for people with advanced solid tumors that have stopped responding to standard treatments. The first part of the study aims to find the safest and most effective dose. The second part will see how w…

This is the first study in people to test a new drug called LB-LR1109. The main goal is to find a safe and tolerable dose for patients with advanced or metastatic solid tumors, including lung, head and neck, kidney, bladder cancers, and melanoma. The study will test the drug alon…

This study is testing if a 'stool transplant' (taking capsules containing processed stool from a healthy donor) can help cancer patients who develop severe diarrhea and colon inflammation from their immunotherapy drugs. Twenty patients with melanoma or kidney cancer will receive …

This study is testing whether a 12-week supervised exercise program can help reduce severe fatigue in adults with advanced melanoma who are receiving immunotherapy or targeted therapy. Researchers will compare a group doing personalized online and in-clinic workouts to a group wi…