New antibody drug targets Hard-to-Treat cancers in first human trial
NCT ID NCT06636435
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a new drug called CBA-1205 in people with advanced solid tumors (like liver cancer or melanoma) that have not responded to other treatments. The main goal is to check the drug's safety and find the best dose. About 66 participants will receive the drug, and researchers will monitor side effects and measure how the body processes the drug.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kanagawa Cancer Center
RECRUITINGYokohama, Kanagawa, 241-8515, Japan
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National Cancer Center Hospital
RECRUITINGChūō, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East
RECRUITINGKashiwa, Chiba, 277-8577, Japan
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Niigata University Medical and Dental Hospital
RECRUITINGNiigata, Niigata, 951-8520, Japan
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University of Yamanashi Hospital
RECRUITINGChūō, Yamanashi, 409-3898, Japan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new infusion drug shrink Hard-to-Treat tumors?
- Can a Tumor's genetic blueprint guide better treatment for kids with brain cancer?
- Can a shorter chemo combo tame High-Risk neuroblastoma?
- Can a 'No-Touch' microwave technique match surgery for liver tumors?
- Can engineered immune cells target a common ovarian cancer protein?