MALE INFERTILITY
Clinical trials for MALE INFERTILITY explained in plain language.
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Can a common breast cancer drug and a supplement boost sperm quality?
Disease control CompletedThis study tested whether letrozole (a drug that lowers estrogen) and L-carnitine (a natural supplement) could improve sperm quality in 90 men with unexplained infertility. Participants took one of the treatments or a combination for three months. The goal was to see changes in s…
Matched conditions: MALE INFERTILITY
Phase: PHASE2, PHASE3 • Sponsor: Tehran University of Medical Sciences • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could a steroid fix male infertility? new trial tests prednisone
Disease control CompletedThis study tested whether a short course of the steroid prednisone could improve sperm quality in men with infertility caused by inflammation. Researchers measured markers of oxidative stress and sperm health six months after treatment. The trial involved 200 men and compared pre…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Sperm vacuoles may reveal hidden DNA damage
Knowledge-focused CompletedThis study looked at 200 men with sperm abnormalities to see if vacuoles (tiny holes) in the sperm head are linked to DNA damage. Researchers used high-powered microscopes and genetic tests to measure vacuole size and chromosome errors. The goal is to help doctors pick healthier …
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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At-Home sperm test could save couples time and worry
Knowledge-focused CompletedThis study looked at whether a simple home semen test can help couples find male fertility problems sooner. About 200 couples who were just starting to try for a baby used a home testing device. The goal was to see if it was easy to use and if it reduced stress while helping coup…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Smaller cut, same hope: study seeks to predict sperm retrieval success
Knowledge-focused CompletedThis study looked at 248 men with very low or no sperm in their semen to see if a less-invasive, mini-incision surgery could successfully retrieve sperm. Researchers checked whether factors like hormone levels or medical history could predict who would benefit from this smaller p…
Matched conditions: MALE INFERTILITY
Sponsor: Clinique Ovo • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Could belly fat be hurting your sperm? new study investigates
Knowledge-focused CompletedThis study examined 170 men from couples struggling with infertility to see if metabolic syndrome—a cluster of conditions like high blood pressure, high blood sugar, and abnormal cholesterol—is linked to poor sperm quality. Researchers measured sperm count and other sperm feature…
Matched conditions: MALE INFERTILITY
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC