MALE INFERTILITY
Clinical trials for MALE INFERTILITY explained in plain language.
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New sperm chip could boost IVF success
Disease control OngoingThis study tests whether a new device called SwimCount Harvester can prepare sperm as well as or better than current methods for couples doing IVF with genetic testing. About 1,600 couples will take part, with the female partner aged 21-45 and the male partner 21 or older. The go…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: MotilityCount aps • Aim: Disease control
Last updated May 17, 2026 08:51 UTC
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Fertility drug showdown: which boosts sperm better?
Disease control ENROLLING_BY_INVITATIONThis study looks at two common fertility drugs—gonadotropin and clomiphene citrate—to see which works better for men with low fertility. About 500 men with abnormal sperm will be randomly assigned to one of the drugs. Researchers will measure sperm count, movement, shape, and DNA…
Matched conditions: MALE INFERTILITY
Phase: PHASE4 • Sponsor: Szeged University • Aim: Disease control
Last updated May 17, 2026 08:48 UTC
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Gene mutation may unlock L-Carnitine's power for sperm health
Disease control OngoingThis study looks at whether men with a specific gene change (TDRD9 mutation) get more improvement in sperm count and movement after taking L-carnitine for three months. About 50 men with low sperm count and slow sperm movement will be tested for the gene and then treated. The goa…
Matched conditions: MALE INFERTILITY
Phase: PHASE3 • Sponsor: South Valley University • Aim: Disease control
Last updated May 17, 2026 08:47 UTC
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Second sperm sample may boost IVF success for men with infertility
Disease control OngoingThis study looks at whether collecting a second sperm sample shortly after the first can provide better quality sperm for ICSI (a type of IVF). The goal is to see if this improves fertilization rates, embryo quality, and pregnancy chances. The trial involves 108 couples where the…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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New sperm test could predict pregnancy chances
Diagnosis OngoingThis study is testing a new sperm test called SpermQT that looks at epigenetic markers to assess sperm quality. Researchers want to see if the test can predict whether couples will get pregnant through treatments like IUI or IVF. The study involves 1,000 couples where the male pa…
Matched conditions: MALE INFERTILITY
Sponsor: Inherent Biosciences • Aim: Diagnosis
Last updated May 13, 2026 16:04 UTC
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Fertility study asks: should embryos be genetically screened for men with no sperm?
Knowledge-focused OngoingThis study looks at 400 couples where the male has a condition called non-obstructive azoospermia (no sperm in the semen). All couples used IVF with a sperm extraction procedure. The researchers want to see if testing embryos for genetic problems (PGT-A) leads to more live births…
Matched conditions: MALE INFERTILITY
Sponsor: Inception Fertility Research Institute, LLC • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Massive biobank launches to unlock secrets of fertility and pregnancy
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a large collection of biological samples and health data from 3,000 people. The goal is to help researchers better understand gynecological disorders, male and female infertility, and pregnancy-related conditions. Participants provide samples and informatio…
Matched conditions: MALE INFERTILITY
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated May 07, 2026 18:38 UTC