MALE INFERTILITY
Clinical trials for MALE INFERTILITY explained in plain language.
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Fertility drug showdown: which boosts sperm better?
Disease control ENROLLING_BY_INVITATIONThis study compares two medications—gonadotropin and clomiphene citrate—to see which better improves sperm health in men with fertility problems. About 500 men with abnormal sperm analysis will be randomly assigned to one of the drugs. The goal is to measure changes in sperm coun…
Matched conditions: MALE INFERTILITY
Phase: PHASE4 • Sponsor: Szeged University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Gene mutation may unlock L-Carnitine's power for sperm health
Disease control OngoingThis study looks at whether men with a specific gene mutation (TDRD9) get more benefit from L-carnitine, a common supplement, to improve sperm count and movement. About 50 men with low sperm count and motility will take L-carnitine for 3 months. Researchers will compare changes i…
Matched conditions: MALE INFERTILITY
Phase: PHASE3 • Sponsor: South Valley University • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New sperm-sorting chip could boost IVF success rates
Disease control OngoingThis study compares a new microfluidic device, SwimCount Harvester, to standard sperm preparation methods in couples undergoing IVF with genetic testing (PGT-A). About 1,600 couples will be randomly assigned to one of the two methods. The goal is to see if the device leads to mor…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: MotilityCount aps • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New sperm test could predict IVF success
Diagnosis OngoingThis study is testing a new sperm quality test called SpermQT. It aims to see if the test can predict how likely a couple is to get pregnant with treatments like IUI or IVF. About 1,000 couples will take part, and researchers will track pregnancy outcomes based on the test result…
Matched conditions: MALE INFERTILITY
Sponsor: Inherent Biosciences • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Which embryo is best? new study aims to boost IVF success
Knowledge-focused OngoingThis study looks at two methods for choosing which embryo to transfer during IVF: the standard way (looking at shape) and a newer way that also tracks how fast the embryo grows. The goal is to see which method leads to more live births. About 520 couples having their first or sec…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Fertility study probes genetic test for men with no sperm in ejaculate
Knowledge-focused OngoingThis study reviews medical records from about 400 couples where the male partner has a condition called non-obstructive azoospermia (NOA), meaning no sperm is found in the semen. All couples used IVF with a special sperm injection technique. The goal is to see if testing embryos …
Matched conditions: MALE INFERTILITY
Sponsor: Inception Fertility Research Institute, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Could a second ejaculate boost IVF success? new trial investigates
Knowledge-focused OngoingThis study looks at whether using sperm from a second ejaculate (collected 1-2 hours after the first) can improve fertilization and embryo quality in ICSI, a type of IVF. Researchers will compare sperm quality and pregnancy outcomes between first and second ejaculates in 108 coup…
Matched conditions: MALE INFERTILITY
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New biobank aims to unlock secrets of infertility and pregnancy
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …
Matched conditions: MALE INFERTILITY
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC