Could a second ejaculate boost IVF success? new trial investigates

NCT ID NCT07056400

Ongoing Knowledge-focused Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether using sperm from a second ejaculate (collected 1-2 hours after the first) can improve fertilization and embryo quality in ICSI, a type of IVF. Researchers will compare sperm quality and pregnancy outcomes between first and second ejaculates in 108 couples where the male partner has abnormal sperm. The goal is to see if this simple change can lead to better results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could offer a simple, non-invasive way to improve ICSI outcomes for couples with male infertility.
What could go wrong: This is a small, early-stage trial with no phase designation. Results may not apply to all infertility cases, and the approach may not significantly improve pregnancy rates.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

male infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALE INFERTILITY

Contacts and locations

Locations

Nour El-Hayat Fertility Center

Cairo, Cairo Governorate, 11762, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.