Could a steroid fix male infertility? new trial tests prednisone
NCT ID NCT01407484
First seen Nov 20, 2025 · Last updated Jun 23, 2026 · Updated 38 times
Summary
This study tested whether a short course of the steroid prednisone could improve sperm quality in men with infertility caused by inflammation. Researchers measured markers of oxidative stress and sperm health six months after treatment. The trial involved 200 men and compared prednisone to a placebo.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cochin Hospital
Paris, 75014, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prednisone (a corticosteroid anti-inflammatory drug)
What this could lead to
If it works, this could point toward a treatment for male infertility caused by inflammation, potentially improving sperm quality and fertility.
What could go wrong
This is a small, early-stage trial with only 200 participants. The treatment is short-term and may not lead to lasting improvement. Risks include side effects from steroids like weight gain or mood changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.