MALARIA,FALCIPARUM

This study tested a new malaria vaccine in 66 healthy adults from Europe and Africa. The vaccine aims to teach the body to fight the malaria parasite. Researchers gave three doses and watched for side effects. The goal was to see if the vaccine is safe enough for further testing.

This study tested a new malaria vaccine (PfSPZ-LARC2) in 75 healthy adults and children in Burkina Faso. The vaccine uses genetically weakened malaria parasites that grow in the liver but cannot cause blood infection. The goal was to see if it is safe and triggers a strong immune…

This study tested a new antibody called TB31F in 167 adults and children in Mali who are often exposed to malaria. The goal was to see if the antibody is safe and can reduce the spread of the malaria parasite to mosquitoes. Participants received either the antibody or a placebo, …

This study tested whether finding and treating low-density malaria infections (infections with very few parasites) in children can improve their long-term health and reduce illness. Researchers followed 600 children in Tanzania, comparing those who received treatment for these hi…

This study tested a new experimental drug called MMV367 in 12 healthy adults who were intentionally infected with the malaria parasite. The goal was to see how the drug works in the body and how well it clears the parasite. Participants were closely monitored and given standard m…

This study tested a new long-acting malaria medicine called MMV371 in 32 healthy adults. The goal was to check if the injection is safe and how the body processes it. Participants received either the medicine or a placebo and were monitored for about 12 weeks. This is an early-st…

This study tested a strategy of rotating four different malaria drugs across 28 health facilities in western Kenya over 28 months. Researchers checked if this approach was practical, affordable, and accepted by patients and health workers. They also tracked genetic changes in mal…