New malaria vaccine shows promise in first human trial in africa

NCT ID NCT06652737

First seen Feb 28, 2026 · Last updated May 01, 2026 · Updated 7 times

Summary

This study tested a new malaria vaccine (PfSPZ-LARC2) in 75 healthy adults and children in Burkina Faso. The vaccine uses genetically weakened malaria parasites that grow in the liver but cannot cause blood-stage infection, aiming to trigger strong immunity safely. The main goal was to check safety and whether the vaccine stays contained in the liver without causing malaria.

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Contacts and locations

Locations

  • Groupe de Recherche Action en Santé (GRAS) / Unité de Recherche Clinique de Sabou

    Ouagadougou, 06, Burkina Faso

Conditions

Explore the condition pages connected to this study.