New antibody could block malaria transmission in High-Risk areas

NCT ID NCT06413108

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a monoclonal antibody called TB31F in 167 adults and children in Mali who are regularly exposed to malaria. The goal was to see if the antibody is safe and can reduce the spread of the malaria parasite from humans to mosquitoes. Participants received either the antibody or a placebo, and researchers measured side effects and how well the antibody worked in blood samples. This is an early-stage trial focused on safety and transmission reduction, not a cure for malaria.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Pharmacy and Faculty of Medicine and Dentistry, University of Sciences Techniques and Technologies of Bamako

    Bamako, Point G, BP1805, Mali

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