Breastfeeding moms with malaria: do drugs reach baby?

NCT ID NCT05676645

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tracks how the malaria drug artemether-lumefantrine passes from a breastfeeding mother into her breastmilk and then into her nursing infant. Researchers will take blood and milk samples from 30 mother-infant pairs in Uganda over two weeks. The goal is to understand drug exposure in infants, which could lead to better dosing guidelines for breastfeeding women.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

artemether-lumefantrine

What this could lead to

If successful, this study could provide data to help doctors choose safe and effective malaria treatments for breastfeeding women and their babies.

What could go wrong

This is a small observational study (30 pairs) that only measures drug levels, not health outcomes. Results may not apply to other malaria drugs or regions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malaria Plasmodium falciparum malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Infectious Diseases Institute

    Kampala, Kampala, 22418, Uganda