MALARIA,FALCIPARUM

This study tests a new malaria vaccine called SUM-101 in 69 healthy children aged 5 months to 5 years in Burkina Faso. The goal is to see if the vaccine is safe and triggers a strong immune response. Researchers will compare different doses to find the best one for future use.

This early-stage study tests whether a new way of giving the R21/Matrix-M™ malaria vaccine is safe and creates a strong immune response. About 36 healthy adults in the UK who have never had malaria will receive either the standard vaccine schedule or an experimental one with incr…

This study tests two experimental malaria vaccines in 360 children aged 5 to 36 months in Burkina Faso, a country where malaria is common. The goal is to see if the vaccines are safe and can prevent malaria illness for at least 6 months after the final dose. Children will receive…

This study tests whether screening pregnant women for malaria during the first trimester using a highly sensitive rapid test, followed by treatment if positive, can reduce serious pregnancy problems like low birth weight, preterm birth, stillbirth, or newborn death. Over 2,000 HI…

This study tests whether giving antimalarial drugs to entire communities, along with targeted treatment for those at highest risk, can reduce malaria transmission in the Sahel region. About 18,000 people in 50 villages in Senegal will take part over two years. The goal is to clea…

This study tests whether giving preventive malaria drugs to school children can reduce malaria and anemia in those children, and also lower the spread of malaria to younger siblings at home. About 1,000 students in rural Malawi will receive either one of two drug combinations or …

This study looks at how common malaria medications travel from a mother's blood into her breastmilk and then to her nursing baby. Researchers will take blood and milk samples from 30 breastfeeding mothers being treated for uncomplicated malaria, plus tiny heel-prick blood samples…