LOCALLY ADVANCED RECTAL CANCER (LARC)
Clinical trials for LOCALLY ADVANCED RECTAL CANCER (LARC) explained in plain language.
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Virus therapy joins Chemo-Radiation in fight against rectal cancer
Disease control Recruiting nowThis early-phase trial tests a new treatment called NG-350A, a virus designed to stimulate the immune system inside tumors, combined with standard chemoradiotherapy for people with locally advanced rectal cancer. The study aims to see if this combination can improve the chance of…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE1 • Sponsor: Akamis Bio • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New combo therapy aims to save rectums in advanced cancer patients
Disease control Recruiting nowThis study tests a new treatment for people with locally advanced rectal cancer that has not spread. The treatment combines short-course radiation, chemotherapy, and two immunotherapy drugs (iparomlimab and tuvonralimab). The goal is to see if this approach can shrink the tumor e…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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New combo therapy aims to save rectums in advanced cancer
Disease control Recruiting nowThis phase 2 trial is testing a new approach for patients with a specific type of locally advanced rectal cancer (MSS-type). Participants will receive a short course of radiation, followed by chemotherapy combined with two additional drugs: serplulimab (an immunotherapy) and beva…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE2 • Sponsor: First Affiliated Hospital of Wenzhou Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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New drug shows promise for rectal cancer patients
Disease control Recruiting nowThis study looks at how well the drug dostarlimab works and how safe it is for people with a certain type of advanced rectal cancer (dMMR/MSI-H). About 50 adults with stage II or III rectal cancer will receive dostarlimab before any other treatment. Researchers will track tumor s…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Sponsor: National Cancer Institute, Naples • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Blood test may predict rectal cancer treatment success
Knowledge-focused Recruiting nowThis study is testing a new blood test that looks for tiny bits of cancer DNA to see if it can predict how well treatment works for people with advanced rectal cancer. Researchers will collect blood and tissue samples from 60 patients before, during, and after treatment. The goal…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Sponsor: Beijing Friendship Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC