New combo therapy aims to shrink rectal tumors before surgery

NCT ID NCT07347951

First seen Jan 18, 2026 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tests a new treatment plan for people with a certain type of locally advanced rectal cancer (MSS-type). The plan combines short-course radiation, chemotherapy, and two drugs (serplulimab and bevacizumab) before surgery. The goal is to see if this approach can eliminate all cancer cells by the time of surgery, potentially allowing more patients to avoid a permanent colostomy. About 30 adults aged 18-75 will take part.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Wenzhou Medical University

    RECRUITING

    Wenzhou, Zhejiang, 325000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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