LOCALLY ADVANCED RECTAL CANCER (LARC)
Clinical trials for LOCALLY ADVANCED RECTAL CANCER (LARC) explained in plain language.
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New drug combo aims to shrink tumors and spare rectums
Disease control Recruiting nowThis study is testing a new treatment approach for people with a common type of advanced rectal cancer. It combines a short course of radiation, standard chemotherapy, and two new immunotherapy drugs to try to shrink tumors before surgery. The main goal is to see if this combinat…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Virus weaponized to fight rectal cancer in new trial
Disease control Recruiting nowThis early-stage trial is testing whether adding a new experimental therapy called NG-350A to standard chemoradiation is safe and effective for people with locally advanced rectal cancer. NG-350A is a specially engineered virus designed to target the tumor and activate the immune…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE1 • Sponsor: Akamis Bio • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Four-Pronged attack on rectal cancer aims to spare patients surgery
Disease control Recruiting nowThis study is testing a new combination of treatments given before surgery for a specific type of rectal cancer. It aims to shrink the tumor as much as possible to improve the chance of curing the cancer and preserving the patient's anus. The treatment involves a short course of …
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE2 • Sponsor: First Affiliated Hospital of Wenzhou Medical University • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Real-World check: can this drug help patients avoid surgery for rectal cancer?
Disease control Recruiting nowThis study aims to see how well the immunotherapy drug dostarlimab works for patients with a specific type of locally advanced rectal cancer in real-world medical practice, not just in a controlled trial. It will follow 50 patients in Italy who are already receiving this treatmen…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Sponsor: National Cancer Institute, Naples • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Blood test could tell doctors if rectal cancer treatment is working
Knowledge-focused Recruiting nowThis study aims to see if a personalized blood test can predict how well pre-surgery treatment works for patients with locally advanced rectal cancer. Researchers will collect blood and tissue samples from 60 patients at different times during their treatment. They will use this …
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Sponsor: Beijing Friendship Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC