LOCALLY ADVANCED RECTAL CANCER (LARC)
Clinical trials for LOCALLY ADVANCED RECTAL CANCER (LARC) explained in plain language.
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New drug cocktail shows promise against tough rectal cancers
Disease control OngoingThis study tests whether adding two immune-boosting drugs (PCSK9 and PD-1 inhibitors) to standard chemoradiation can help shrink or eliminate locally advanced rectal cancer. It involves 30 adults aged 18-75 with a specific type of rectal cancer (pMMR/MSS) that has not spread. The…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: PHASE2 • Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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Radiation-Free hope: new combo tackles tough rectal cancer
Disease control OngoingThis study tests a new approach for people with locally advanced rectal cancer that has a specific genetic profile (MSS/pMMR). Instead of standard radiation, participants receive a combination of chemotherapy (mFOLFOX6) and an immunotherapy drug (PD-1 antibody) before surgery. Th…
Matched conditions: LOCALLY ADVANCED RECTAL CANCER (LARC)
Phase: NA • Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated May 12, 2026 13:43 UTC