LOCALLY ADVANCED BREAST CANCER
Clinical trials for LOCALLY ADVANCED BREAST CANCER explained in plain language.
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New hope for Tough-to-Treat breast cancer: experimental combo enters human trials
Disease control OngoingThis study is testing whether adding a new, experimental drug called onvansertib to a standard chemotherapy (paclitaxel) is safe and effective for people with triple-negative breast cancer that has spread. The first part finds the safest dose, and the second part checks if the co…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Antonio Giordano, MD • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for Tough-to-Treat breast cancer
Disease control OngoingThis study is testing a new drug called BNT327, given alongside standard chemotherapy, for people with advanced triple-negative breast cancer. The main goals are to see if the combination is safe and if it helps shrink tumors. The trial will enroll about 83 adults who have either…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New hope for advanced breast cancer? trial tests potential cheaper alternative
Disease control OngoingThis study is testing if a new drug called RPH-051 works as well as the established drug Perjeta (pertuzumab) for controlling advanced HER2-positive breast cancer. About 246 patients with metastatic or locally advanced cancer will receive either RPH-051 or Perjeta, combined with …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE3 • Sponsor: R-Pharm • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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Radiation 'Primer' tested to boost chemo power against aggressive breast cancer
Disease control OngoingThis study is testing if giving a short, targeted course of radiation before standard chemotherapy can improve treatment results for people with high-risk breast cancer. The radiation aims to 'prime' the immune system to help the body fight the cancer. Researchers will measure if…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC
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New study aims to improve breast cancer surgery decisions
Diagnosis OngoingThis study is testing how well a lymph node biopsy procedure works for women with advanced breast cancer who have already received chemotherapy. Researchers want to see if this less invasive test can accurately detect any remaining cancer cells after treatment. The goal is to hel…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated Mar 27, 2026 12:39 UTC