LOCALLY ADVANCED BREAST CANCER
Clinical trials for LOCALLY ADVANCED BREAST CANCER explained in plain language.
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New hope for hard-to-treat breast cancer: experimental combo shows promise
Disease control OngoingThis study tests a new drug called BNT327, given with chemotherapy, for people with advanced triple-negative breast cancer that has spread. The goal is to see if the combination is safe and shrinks tumors. About 83 adults will take part, and the study is currently active but not …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Radiation before chemo: a new strategy to fight High-Risk breast cancer?
Disease control OngoingThis trial is testing whether giving a small dose of targeted radiation to a part of the breast tumor before standard chemotherapy can help the immune system fight the cancer more effectively. The study includes 40 people with high-risk or locally advanced breast cancer. After ra…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New drug combo aims to shrink tough breast cancer tumors
Disease control OngoingThis study tests whether adding the experimental drug onvansertib to standard chemotherapy (paclitaxel) can safely shrink tumors in people with triple-negative breast cancer that has spread. About 50 adults with advanced or metastatic disease will receive the combination. The goa…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Antonio Giordano, MD • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New hope for advanced breast cancer: could a biosimilar match the standard?
Disease control OngoingThis study tests whether a new drug called RPH-051 works as well as the approved drug Perjeta when both are given with standard chemotherapy and another targeted therapy for people with HER2-positive breast cancer that has spread or cannot be removed. About 246 participants will …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE3 • Sponsor: R-Pharm • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Can a simple biopsy replace major surgery after breast cancer chemo?
Knowledge-focused OngoingThis study looks at whether a sentinel lymph node biopsy (a less invasive procedure) can accurately find leftover cancer cells after chemotherapy in women with locally advanced breast cancer. Researchers will compare the biopsy results to the standard full lymph node removal. The…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC