LOCALLY ADVANCED BREAST CANCER
Clinical trials for LOCALLY ADVANCED BREAST CANCER explained in plain language.
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New combo drug trial aims to stall advanced breast cancer
Disease control CompletedThis study tested whether adding an experimental drug called samuraciclib to the standard hormone therapy fulvestrant could better control advanced breast cancer that has stopped responding to prior treatments. It involved 60 adults with hormone receptor-positive, HER2-negative b…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: Carrick Therapeutics Limited • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug duo tested for tough-to-treat breast cancer
Disease control CompletedThis study tested whether combining two drugs, samuraciclib and elacestrant, is safe and effective for people with advanced hormone-positive, HER2-negative breast cancer that has progressed on standard therapy. It involved 49 adult participants internationally. The trial first ai…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Carrick Therapeutics Limited • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New Triple-Threat treatment tested for tough breast cancers
Disease control CompletedThis study tested whether combining three medications—olaparib, palbociclib, and fulvestrant—is safe for people with advanced breast cancer that is hormone-sensitive and has a BRCA gene mutation. The main goal was to check for side effects and see how long patients lived without …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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New drug tested to fight advanced breast cancer
Disease control CompletedThis study tested a new drug called U3-1402 in 121 patients whose breast cancer had spread or was locally advanced. The main goal was to see if the drug was safe and if it could shrink tumors or stop the cancer from growing for at least six months. Researchers also looked at how …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: SCRI Development Innovations, LLC • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Cancer patients overwhelmingly prefer home treatment, major study finds
Disease control CompletedThis study aimed to find out if patients with a specific type of breast cancer (HER2-positive) preferred receiving a two-drug treatment at home or in a hospital. Over 300 participants tried both methods. The main goal was to measure which setting patients liked better, focusing o…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Mar 02, 2026 15:23 UTC