KNEE ARTHRITIS
Clinical trials for KNEE ARTHRITIS explained in plain language.
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Knee replacement pain relief: which drug works better?
Symptom relief CompletedThis study tested whether adding dexamethasone or dexmedetomidine to a nerve block (ESPB) could help control pain after total knee replacement. 90 adults having knee surgery took part. The main goal was to see which drug helped delay the first time a patient needed strong opioid …
Matched conditions: KNEE ARTHRITIS
Phase: PHASE4 • Sponsor: Poznan University of Medical Sciences • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Steroid taper after knee surgery may ease pain and nausea
Symptom relief CompletedThis study tested whether a short course of steroids (Medrol Dose Pak) given after total knee replacement can reduce pain, nausea, and the need for painkillers. About 100 adults with knee arthritis took part. The goal was to see if this simple anti-inflammatory treatment helps pe…
Matched conditions: KNEE ARTHRITIS
Phase: PHASE4 • Sponsor: Emory University • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New nerve block eases knee surgery pain without affecting movement
Symptom relief CompletedThis study tested a special nerve block called PSKB to control pain after knee surgery. The goal was to provide good pain relief without weakening leg muscles, so patients could move sooner. Sixty adults having knee surgery took part. The study measured pain levels and the need f…
Matched conditions: KNEE ARTHRITIS
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New pain block study aims to cut opioid use after knee surgery
Symptom relief CompletedThis study compared two different nerve block techniques to manage pain after total knee replacement surgery. Sixty adults with knee arthritis took part. The goal was to see which method better reduces the need for strong painkillers (opioids) and improves pain scores in the firs…
Matched conditions: KNEE ARTHRITIS
Phase: PHASE4 • Sponsor: Poznan University of Medical Sciences • Aim: Symptom relief
Last updated May 11, 2026 20:53 UTC
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New knee injection shows promise for arthritis sufferers
Symptom relief CompletedThis study tested a single injection of TTAX03 in 90 adults with severe knee osteoarthritis (grades 3-4). The goal was to see if it reduces pain and improves function better than a placebo (saline) injection after 12 weeks. Researchers measured how many people felt at least a 20-…
Matched conditions: KNEE ARTHRITIS
Phase: PHASE2 • Sponsor: BioTissue Holdings, Inc • Aim: Symptom relief
Last updated May 08, 2026 12:04 UTC