KIDNEY TRANSPLANTATION

This study tests whether personalized education and regular phone counseling can help kidney transplant recipients take their anti-rejection medication as prescribed. Sixty adult kidney transplant patients will be split into two groups: one receives the extra support, the other g…

This study looks at a drug called imlifidase that temporarily removes harmful antibodies from the blood, allowing highly sensitized kidney patients to receive a transplant from a donor they would otherwise reject. About 450 adults who are unlikely to get a kidney through standard…

This study tests whether a lower dose of the antibiotic TMP-SMX works as well as the standard dose to prevent a serious lung infection called PJP in people who have just had a kidney transplant. About 1,084 adult first-time kidney transplant recipients will take either a low or s…

This study compares a new tubeless anesthesia method to standard breathing-tube anesthesia for kidney transplant patients. The goal is to see if the tubeless approach reduces the amount of muscle relaxants and other drugs needed, and whether it leads to faster recovery. Sixty adu…

This study looks at how a common virus called CMV changes the immune system in people who have had a kidney transplant. Researchers will compare immune responses in 60 patients, some with and some without CMV infection. The goal is to understand which immune pathways are affected…

This study will develop and test new MRI methods to examine the kidneys and brain in people with chronic kidney disease, kidney transplants, or on dialysis. Researchers hope to find better ways to diagnose and track kidney problems and understand why kidney disease often leads to…

This study looks at how living kidney donors feel about receiving a symbolic award, like a commemorative medal, after their donation. Researchers will interview 15 donors to understand their motivations and whether such recognition improves their experience. The goal is to find r…

This study looks at whether muscle ultrasound can accurately measure muscle loss (sarcopenia) in people receiving a kidney transplant. About 140 adult patients will have ultrasound and a standard body composition test before and after transplant. The goal is to see if ultrasound …

This study aims to understand how BK virus spreads in people who have received a kidney transplant. Researchers will collect saliva, urine, and blood samples from 100 adult kidney transplant recipients at several time points over one year. By measuring the virus in these samples,…

This study follows 150 adults waiting for a kidney transplant to see how their physical strength and emotional well-being change over time. Researchers will use a mobile app to collect regular health reports directly from patients and conduct interviews to understand their experi…

This study creates a flexible 'platform' to test many different treatments for advanced kidney disease at once, making research faster and cheaper. It will include up to 5,000 adults with severe kidney problems, including those on dialysis or with a kidney transplant. The goal is…