INVASIVE BREAST CARCINOMA

This study tested whether a shorter, more intense 9-day radiation schedule works as well as the standard 6-8 week treatment for early-stage breast cancer. It involved 102 patients who had undergone lumpectomy, aiming to see if the shorter treatment controls cancer equally while p…

This study tested a two-drug combination given before surgery to treat triple-negative breast cancer, a type that can be harder to treat. It involved 37 patients whose cancer did not shrink enough after standard initial chemotherapy. The goal was to see if adding an immunotherapy…

This early-stage study tested the safety and best dose of two oral drugs, abemaciclib and niraparib, given together before surgery for certain types of breast cancer. The goal was to see if this combination could shrink tumors effectively with manageable side effects. The study i…

This study tested whether injecting a specially modified cold sore virus directly into breast tumors during chemotherapy before surgery could help eliminate cancer more effectively. The virus is designed to attack cancer cells and may help the patient's own immune system fight th…

This study tested whether adding the hormone therapy fulvestrant to a new drug called alisertib works better than alisertib alone for women with advanced breast cancer that has spread and stopped responding to standard hormone treatments. It involved 96 postmenopausal women. Rese…

This study tested whether a special type of mammogram, which uses a contrast dye injected into the vein, is better at finding all areas of breast cancer in women who were getting a second opinion at a major cancer center. The goal was to see if this method could find cancers that…