New combo shrinks hard-to-treat breast tumors before surgery

NCT ID NCT02689427

First seen May 13, 2026 ยท Last updated May 13, 2026

Summary

This study tested a combination of enzalutamide (a hormone blocker) and paclitaxel (chemotherapy) given before surgery to people with a specific type of triple-negative breast cancer that has androgen receptors. The goal was to see if this treatment could shrink tumors and reduce the amount of tissue that needs to be removed. 24 adults with stage I-III breast cancer took part. The approach aims to control the disease and improve surgical outcomes.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • MD Anderson West Houston

    Houston, Texas, 77079, United States

Conditions

Explore the condition pages connected to this study.