INSOMNIA DISORDER

This phase 3 study tests whether YZJ-1139 tablets help adults with insomnia fall asleep faster and sleep more efficiently. Participants receive either 20 mg, 40 mg, or a placebo daily for two weeks. Sleep is measured using both sleep diaries and overnight lab tests.

This clinical trial tests whether a new drug called YZJ-1139 can help people with insomnia sleep better than the commonly used medication zolpidem. Adults aged 18 to 64 with insomnia disorder take either YZJ-1139 or zolpidem daily for 28 days. Researchers measure sleep quality us…

This study tested a six-session behavioral sleep program, called Apnea and Insomnia Relief (AIR), in 118 Gulf War veterans with Gulf War Illness. The program combined sleep education, motivation for using a breathing machine, and insomnia therapy, all done via telehealth. Researc…

This study tested whether a Persian-language internet program called Omid, based on cognitive behavioral therapy, can improve sleep in adults with insomnia. Thirty participants were randomly assigned to use the program or receive usual care. The program includes weekly online les…

This small study tested whether combining digital cognitive behavioral therapy for insomnia (CBT-I) with sessions in a sauna blanket is feasible for adults with insomnia. Ten participants used an online CBT-I program and a sauna blanket at home for 9 weeks. The goal was to see if…

This study tested an online program called SLEEPexpert that teaches behavioral techniques to improve sleep in people with mental disorders. 68 psychiatric inpatients with insomnia used the program alongside their usual treatment. The goal was to see if it helps reduce insomnia an…

This study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep also improves quality of life and daily functioning. Participants attended therapy sessions and reported their sleep and well-being throu…

This study tested whether adding a virtual coach (phone support) helps veterans with insomnia use a digital cognitive behavioral therapy program for sleep. 244 veterans were randomly assigned to either the digital program with coaching or with minimal contact. The goal was to see…

This study tested a new sleep medication called daridorexant in 164 adults and elderly people with insomnia. Participants received either the drug or a placebo for 4 weeks. Researchers measured changes in total sleep time, how fast they fell asleep, and time awake after sleep ons…

This study tested whether a culturally adapted version of cognitive behavioral therapy for insomnia (CBTi) could help Arab adults sleep better. 54 participants were randomly assigned to receive one of two adapted therapy versions or be placed on a waitlist. The goal was to see if…

This study tested a program to improve sleep and daytime activity in frail adults aged 65 and older with insomnia. Seven participants tried a 24-hour approach to build healthier sleep-wake habits. The goal was to see if the program was practical and well-liked, and to measure cha…