INFERTILITY (IVF PATIENTS)

This phase 3 trial tests whether a daily injection of human menopausal gonadotropin (hMG) can help women with infertility develop more eggs and achieve a live birth during IVF. About 659 women aged 18-42 will receive either the hormone or a placebo. The main goal is to see if the…

This study tests whether using special devices during embryo transfer can help more IVF patients get pregnant. The devices keep the embryo at the right temperature and control the transfer process to reduce human error. About 160 women having frozen embryo transfers will be rando…

This study tests whether giving growth hormone or DHEA (a natural hormone) can improve egg production and pregnancy rates in women with poor ovarian reserve who are undergoing IVF. 165 women will receive one of these treatments or a placebo (folic acid only) for 1-3 months before…

This study tests whether giving the painkiller ketorolac after egg retrieval can safely reduce pain without lowering the chance of pregnancy in fresh embryo transfers. About 200 IVF patients will be randomly assigned to receive either ketorolac or no ketorolac after their egg ret…

This study tests a computer tool called Opt-IVF that creates personalized drug plans for women undergoing IVF. The goal is to improve the number and quality of eggs and embryos retrieved. About 200 infertile women will participate to see if this tailored approach leads to better …

This study looks at why some people's fertility treatments don't work. Researchers will follow 5,000 infertile patients (half men, half women) to see how things like pollution from plastics, daily habits, and social factors affect the chance of having a baby through treatments li…

This study is developing an artificial intelligence (AI) platform to analyze sperm samples and predict how likely they are to lead to a successful pregnancy during IVF. Researchers will collect and study 500 semen samples from men undergoing IVF, using AI to look for patterns tha…

This study is creating a biobank of male biological samples, such as sperm and testicular tissue, from men undergoing fertility treatments. The goal is to collect and store these samples for future research on male infertility and assisted reproductive technologies. Up to 1,000 p…

This study looks at how the age of the male partner and the way sperm is chosen might affect embryo growth in IVF. About 100 couples having their first IVF cycle will take part. Researchers will compare a special sperm selection device (Zymot) with the usual method to see which l…

This pilot study uses a special ultrasound technique called shear wave elastography to measure how stiff the uterus, cervix, and ovaries are in women with and without fertility problems. Researchers will track changes across the menstrual cycle in 40 women to establish normal ran…

This study looks at whether measuring telomeres—parts of our cells linked to aging—can help explain why some women still can't get pregnant even after fertility treatments. Fifteen women aged 25 to 42 will get blood tests to check their biological age, then receive a personalized…

This study looks at whether transferring embryos after 3 days or 5 days leads to more live births in IVF patients who have 5 or fewer embryos. About 1,126 people will take part, and researchers will also track patient satisfaction and complications. The goal is to help doctors an…

This study is testing whether an artificial intelligence (AI) tool can help people undergoing IVF treatment stay engaged and follow their doctor's recommendations. Researchers will enroll 774 infertility patients aged 18-45 in Portugal. The goal is to see if personalized AI guida…

This study compares two hormone protocols used during IVF to see which leads to better embryo development. About 148 women will be randomly assigned to receive either a fixed PPOS protocol or a GnRH antagonist protocol. Embryos will be monitored with a special time-lapse incubato…

This study uses artificial intelligence to analyze vaginal ultrasound images of the uterine lining taken during routine IVF treatment. The goal is to see if the AI can predict whether an embryo will successfully implant. Researchers will enroll 1,500 women aged 18-40 undergoing I…