HYPOVOLEMIA
Clinical trials for HYPOVOLEMIA explained in plain language.
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Leg lift test may help ICU doctors avoid unnecessary fluids
Diagnosis CompletedThis study tested whether changes in pulse pressure during a passive leg raise can predict if a patient needs fluids. Researchers included 39 spontaneously breathing ICU patients with signs of low blood flow. They measured pulse pressure and its variation before and after a leg r…
Matched conditions: HYPOVOLEMIA
Sponsor: CHU de Reims • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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Pre-Surgery hydration strategy cuts blood pressure drop risk
Prevention CompletedThis study tested whether giving patients a personalized amount of IV fluids before surgery could prevent dangerously low blood pressure after anesthesia. 110 women undergoing gynecological pelvic surgery were randomly assigned to receive either weight-based fluids or standard fa…
Matched conditions: HYPOVOLEMIA
Phase: NA • Sponsor: Mustafa Burgac • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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Can a simple monitor predict fluid needs in critically ill kids?
Knowledge-focused CompletedThis study tests whether a device called Mostcare can predict if children need more fluids after surgery. Researchers will compare its readings with ultrasound measurements in 100 children aged 0-10 who are on breathing machines. The goal is to see if the device can help doctors …
Matched conditions: HYPOVOLEMIA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 02, 2026 02:00 UTC
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Fluid bolus study reveals how IV fluids impact heart and brain in low blood volume
Knowledge-focused CompletedThis completed study in 15 healthy volunteers tested how a small amount of Ringer's acetate (a common IV fluid) affects heart function and brain blood flow when blood volume is low. Participants were given the fluid during both normal and low blood volume conditions (simulated us…
Matched conditions: HYPOVOLEMIA
Phase: PHASE4 • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Ultrasound test may help doctors avoid giving too much fluid to sick children
Knowledge-focused CompletedThis study tested whether ultrasound measurements of the heart and blood vessels can predict which mechanically ventilated children will benefit from extra fluids. Only about half of children with shock respond to fluids, and too much fluid can be harmful. The researchers used a …
Matched conditions: HYPOVOLEMIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Can tilting the bed improve pain detection in surgery?
Knowledge-focused CompletedThis study looked at whether changing a patient's body position during surgery affects a device called the Analgesia Nociception Index (ANI), which is used to measure pain under anesthesia. Thirty neurosurgery patients were monitored as their bed was tilted head-up or head-down. …
Matched conditions: HYPOVOLEMIA
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Does surgery fluid choice matter? new study investigates blood vessel protection
Knowledge-focused CompletedThis study looked at how two different amounts of IV fluids given during lung surgery affect a protective layer inside blood vessels called the glycocalyx. Researchers measured markers of vessel damage in 41 patients who received either a low or high rate of fluid. The goal was t…
Matched conditions: HYPOVOLEMIA
Phase: NA • Sponsor: Kocaeli Derince Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Fasting before surgery: safe or risky? new study checks blood volume
Knowledge-focused CompletedThis study looked at whether not eating before surgery (preoperative fasting) causes low blood volume. Researchers used heart ultrasound to measure blood volume changes in 100 patients before and after fasting. The goal was to see if fasting increases the chance of low blood volu…
Matched conditions: HYPOVOLEMIA
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC