HPV-RELATED CARCINOMA
Clinical trials for HPV-RELATED CARCINOMA explained in plain language.
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New combo therapy shows promise against HPV-Driven cancers
Disease control OngoingThis study tests whether combining two drugs—TG4001 (a vaccine-like therapy) and avelumab (an immunotherapy)—can shrink tumors or slow disease in people with advanced HPV-16 cancers (cervical, anal, penile, vulvar, or vaginal). About 143 adults whose cancer has spread or returned…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Transgene • Aim: Disease control
Last updated May 17, 2026 05:34 UTC
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Healthy donors vaccinated against HPV to help fight cancer in loved ones
Disease control ENROLLING_BY_INVITATIONThis study enrolls healthy relatives of patients with advanced HPV16-related cancer. Donors receive a therapeutic HPV vaccine to boost their immune cells against the virus. Their blood cells are then used for a bone marrow transplant or immune cell infusion in the cancer patient.…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Personalized T-Cell army takes on Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests a new treatment called T-Plex for people with advanced solid tumors that have not responded to standard therapies. The treatment uses a patient's own immune cells, which are modified in a lab to recognize and attack multiple cancer-related targets. Th…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1 • Sponsor: TScan Therapeutics, Inc. • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New HPV cancer drug enters human testing
Disease control OngoingThis early-stage study tests a new drug called IBRX-042 in people with HPV-related cancers that have come back or gotten worse. The main goals are to find the safest dose and see what side effects occur. Twelve participants will receive three injections of the drug, one every thr…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1 • Sponsor: ImmunityBio, Inc. • Aim: Disease control
Last updated Apr 23, 2026 12:44 UTC
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Blood test may sniff out hidden throat cancer before symptoms start
Diagnosis OngoingThis study is testing whether a blood test called NavDx can find early signs of HPV-related throat cancer by looking for tiny pieces of HPV DNA in the blood. The researchers are enrolling adults aged 45 and older who have had multiple sexual partners. The goal is to see how many …
Matched conditions: HPV-RELATED CARCINOMA
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated May 11, 2026 20:38 UTC