HPV-RELATED CARCINOMA
Clinical trials for HPV-RELATED CARCINOMA explained in plain language.
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Tailored radiation beams aim to outsmart aggressive throat cancer
Disease control OngoingThis pilot study tests a personalized radiation plan for people with HPV-related throat cancer that is considered high-risk. Using advanced scans (MRI and PET), doctors adjust the radiation dose to target the most aggressive parts of the tumor. The goal is to see if this approach…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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HPV vaccine in healthy donors could help fight cancer
Disease control ENROLLING_BY_INVITATIONThis early-phase trial tests an HPV vaccine series in healthy relatives of patients with advanced HPV-related cancer. The goal is to generate HPV-specific white blood cells that can be collected and used in a bone marrow transplant or donor lymphocyte infusion for the patient. Th…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Experimental combo targets Hard-to-Treat HPV cancers
Disease control OngoingThis study tests a combination of two drugs—TG4001 (a biologic that targets HPV) and avelumab (an immunotherapy)—in people with advanced HPV-16 cancers that cannot be removed by surgery or cured by radiation. The trial has two phases: first, to find a safe dose, and second, to se…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Transgene • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Custom immune cells take on multiple cancers in early trial
Disease control OngoingThis early-stage study tests a new treatment called T-Plex for people with advanced solid tumors (like head and neck, cervical, or melanoma) that haven't responded to standard therapies. The treatment uses a patient's own immune cells, which are modified in a lab to recognize and…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1 • Sponsor: TScan Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New HPV cancer drug IBRX-042 enters first human safety trial
Disease control OngoingThis early-stage trial tests a new drug called IBRX-042 in 12 people with HPV-related cancers that have come back or worsened. The main goal is to find the safest dose and understand side effects. Participants get three injections, one every three weeks, and are closely monitored…
Matched conditions: HPV-RELATED CARCINOMA
Phase: PHASE1 • Sponsor: ImmunityBio, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Simple blood test could spot hidden throat cancer
Diagnosis OngoingThis study is testing whether a blood test called NavDx can find HPV-related oropharyngeal cancer early by looking for HPV DNA in the blood. Researchers are enrolling adults aged 45 and older with multiple sexual partners who have no history of this cancer. Participants give bloo…
Matched conditions: HPV-RELATED CARCINOMA
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated Jun 26, 2026 19:16 UTC