HPV INFECTION

This study looks at whether a 2-dose HPV vaccine (Gardasil 9) works as well as the standard 3-dose schedule in women aged 16 to 45. About 352 women at Boston Medical Center will receive the 2-dose regimen, and researchers will measure their immune response over 6 months. The goal…

This study looks at whether giving a smaller (one-fifth) dose of the HPV vaccine can still trigger a strong immune response in adults aged 27 to 45. Researchers are comparing two types of HPV vaccines and two ways of giving the shot (into the skin or into the muscle). The goal is…

This study aims to find the most effective screening method for detecting early signs of cervical cancer in women living with HIV in Latin America. Researchers will compare different tests (cervical swabs, self-collected vaginal swabs, urine tests, and biopsies) on 1,002 particip…

This study tests a fun, game-based program to help families with kids aged 11-14 decide about the HPV vaccine. The goal is to see if the game is easy to use and if it increases vaccination rates. About 131 families will take part, and the hope is to reduce future cancers caused b…

This study looks at whether giving a single dose of the HPV vaccine to teenage boys, on top of the existing program for girls, can lower the number of HPV infections in the whole community. About 10,400 people in 26 communities in northern Tanzania are taking part. Researchers wi…

This study tests whether the nine-valent HPV vaccine can prevent persistent oral HPV infections in 700 men living with HIV. Participants receive either the vaccine or a placebo and are followed for up to four years. The goal is to see if the vaccine reduces the risk of HPV-relate…

This study tests a new online program called ORCHID, designed to help aging women with HIV feel better emotionally and stay in care. The program teaches skills to build positive feelings and cope with stress. Researchers will enroll 30 women from a Miami HIV clinic to see if the …

This study looks at how common high-risk HPV is in transgender people by having them collect their own samples from the vagina, anus, urine, and mouth. Transgender men will also have a clinician-collected cervical swab to compare accuracy. The goal is to make HPV screening more c…

This study looks at how well vaginal self-sampling works for detecting high-risk HPV in women aged 30-65 who have immune-mediated inflammatory diseases like lupus or Sjögren's syndrome. Researchers will track HPV infection rates, types, and clearance over one year. The goal is to…