Could At-Home HPV tests improve screening for transgender people?

NCT ID NCT05883111

Ongoing Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether transgender individuals can collect their own samples for HPV testing at home or in a clinic. Researchers want to learn how common high-risk HPV is in this group and whether self-sampling is acceptable and effective. About 100 transgender men and women will take swabs from the vagina, anus, urine, and mouth, and complete a survey about their experience.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: HPV DNA methylation assay
What this could lead to: If successful, this could show that self-sampling is a practical and acceptable way to screen transgender people for HPV, potentially increasing screening rates and catching cancer early.
What could go wrong: This is a small pilot study (100 people) focused on feasibility, not on health outcomes. It may not prove that self-sampling is as accurate as clinician-collected samples, and results may not apply to all transgender populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HPV INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

human papilloma virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HPV INFECTION

Contacts and locations

Locations

Ambrose King Centre, Barts Health NHS Trust

London, United Kingdom
CliniQ, Caldicott Centre, Kings College Hospitals

London, United Kingdom
University Hospitals Sussex NHS Foundation Trust Sexual Health Service

Brighton, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.