Could At-Home HPV tests improve screening for transgender people?
NCT ID NCT05883111
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether transgender individuals can collect their own samples for HPV testing at home or in a clinic. Researchers want to learn how common high-risk HPV is in this group and whether self-sampling is acceptable and effective. About 100 transgender men and women will take swabs from the vagina, anus, urine, and mouth, and complete a survey about their experience.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HPV DNA methylation assay
What this could lead to
If successful, this could show that self-sampling is a practical and acceptable way to screen transgender people for HPV, potentially increasing screening rates and catching cancer early.
What could go wrong
This is a small pilot study (100 people) focused on feasibility, not on health outcomes. It may not prove that self-sampling is as accurate as clinician-collected samples, and results may not apply to all transgender populations.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ambrose King Centre, Barts Health NHS Trust
London, United Kingdom
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CliniQ, Caldicott Centre, Kings College Hospitals
London, United Kingdom
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University Hospitals Sussex NHS Foundation Trust Sexual Health Service
Brighton, United Kingdom