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Can a daily supplement help the body fight off HPV?

NCT ID NCT07697196

Not yet recruiting Disease control Sponsor: IRCCS San Raffaele Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study tests whether a daily oral supplement containing green tea extract (EGCG), folic acid, vitamin B12, and hyaluronic acid can help women clear a persistent human papillomavirus (HPV) infection. HPV is a common virus that can cause cervical cancer if it stays in the body for a long time. The trial involves 42 women aged 25 and older who have had HPV for at least 9 months and have low-grade cervical changes. Half will take the supplement for six months, while the other half receive standard care. Researchers will measure whether the virus's activity in cells decreases, which could indicate the body is clearing the infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pervistop (epigallocatechin gallate, folic acid, vitamin B12, hyaluronic acid)
What this could lead to
If effective, this supplement could offer a simple, non-invasive way to help the body clear persistent HPV and reduce the risk of cervical cancer.
What could go wrong
This is a small early-stage trial with only 42 participants, so results may not apply broadly. Dietary supplements are not regulated as strictly as drugs, and the effect may be modest or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anogenital human papillomavirus infection cervical squamous intraepithelial neoplasia human papilloma virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HPV DISEASE HPV GENITAL INFECTION HPV INFECTION HPV INTEGRATION HPV PERSISTENCE LOW GRADE SQUAMOUS INTRAEPITHELIAL LESIONS OF THE CERVIX

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS San Raffele Hospital

    Milan, Italy, 20100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

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