Could two HPV shots be enough? new study tests simpler vaccine schedule
NCT ID NCT04206813
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a 2-dose schedule of the HPV vaccine (Gardasil 9) is as effective as the standard 3-dose schedule in women aged 16 to 45. Researchers will measure antibody levels in 352 women to compare immune responses. If the 2-dose regimen works well, it could simplify vaccination and reduce costs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gardasil 9 (HPV vaccine)
What this could lead to
If successful, this could show that a 2-dose HPV vaccine schedule is effective for women up to age 45, making vaccination simpler and cheaper.
What could go wrong
This is a small, single-center study, not a large Phase 3 trial. The results may not apply to all populations, and the 2-dose schedule might not provide long-term protection as strong as 3 doses.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Medical Center
Boston, Massachusetts, 02118, United States