Could mixing HPV vaccines offer better protection?

NCT ID NCT07281677

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether giving girls aged 9-14 two different HPV vaccines in a sequence is safe and boosts immunity. The researchers will measure antibody levels and side effects in 400 participants. The goal is to see if this approach can improve protection against HPV, which causes cervical cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HPV vaccines (bivalent and 9-valent)

What this could lead to

If successful, this could show that using different HPV vaccines in sequence is a safe and effective way to protect against more types of HPV, potentially improving cervical cancer prevention.

What could go wrong

This is a Phase 4 study with 400 girls, so results may not apply to all populations. The main focus is on immune response and safety, not long-term cancer prevention, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

human papilloma virus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jinyun center for Disease Control and Prevention

    Lishui, Zhejiang, 321400, China