HGG
Clinical trials for HGG explained in plain language.
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Helmet uses sound waves to open Brain's barrier for cancer drugs
Disease control Recruiting nowThis early-stage study is testing whether a special helmet that uses focused ultrasound can safely and temporarily open the blood-brain barrier in adults with glioblastoma. The goal is to help standard chemotherapy drugs reach the brain tumor more effectively. Researchers will en…
Matched conditions: HGG
Phase: PHASE1 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New targeted pill aims to shrink tough tumors with specific genetic flaw
Disease control Recruiting nowThis study is testing an oral drug called plixorafenib (FORE8394) for people with advanced solid tumors or brain tumors that have specific changes in a gene called BRAF. The main goal is to see if the drug can shrink tumors and is safe for patients, including adults and children …
Matched conditions: HGG
Phase: PHASE2 • Sponsor: Fore Biotherapeutics • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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New pill combo targets tough cancers in early trial
Disease control Recruiting nowThis early-stage study is testing the safety and initial effects of a new oral medicine, PF-07799544, when taken with another drug, PF-07799933. It is for adults with advanced solid tumors, like melanoma or lung cancer, that have a specific genetic change called a BRAF V600 mutat…
Matched conditions: HGG
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated Mar 04, 2026 15:30 UTC