HGG
Clinical trials for HGG explained in plain language.
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Sound wave helmet could help chemo reach brain tumors
Disease control Recruiting nowThis early-stage trial tests a special helmet that uses sound waves to temporarily open the blood-brain barrier, allowing chemotherapy to better reach aggressive brain tumors called glioblastoma. Ten adults who have already completed initial treatment will receive the helmet trea…
Matched conditions: HGG
Phase: PHASE1 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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New drug targets Hard-to-Treat BRAF cancers in Mid-Stage trial
Disease control Recruiting nowThis study tests a drug called FORE8394 (plixorafenib) in people aged 10 and older with advanced solid tumors or brain tumors that have specific BRAF gene changes. The goal is to see if the drug can shrink tumors and control the disease. About 254 participants will take the drug …
Matched conditions: HGG
Phase: PHASE2 • Sponsor: Fore Biotherapeutics • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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New pill combo targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis study tests a new experimental drug (PF-07799544) combined with another drug (PF-07799933) in adults with advanced solid tumors that have a specific gene change called BRAF V600. The goal is to see if the combination is safe and can shrink or control the cancer. Participants…
Matched conditions: HGG
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated May 06, 2026 16:13 UTC
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Glowing drug lights up brain tumors during surgery
Knowledge-focused Recruiting nowThis study tests a special version of the cancer drug nivolumab that has a fluorescent dye attached, called nivo800. The dye makes the drug glow, so doctors can see where it collects in brain tumors during surgery. The goal is to learn if this is safe and helps surgeons see tumor…
Matched conditions: HGG
Phase: EARLY_PHASE1 • Sponsor: Eben Rosenthal • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC