Experimental brain cancer drug NRG-103 enters first human tests
NCT ID NCT07710690
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This early-stage trial tests an experimental drug called NRG-103 in about 24 adults with recurrent or progressive high-grade glioma, an aggressive brain cancer. The main goals are to find a safe dose and check for side effects, while also looking for early signs that the drug might help control the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental drug called NRG-103
- What this could lead to
- If it works, this could point toward a new treatment option for people with recurrent high-grade glioma, a type of aggressive brain cancer.
- What could go wrong
- This is a very early, small Phase 1 trial focused on safety and dosing, so it is far from proving effectiveness. The drug may not work or could have serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HGG are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Huashan Hospital Affiliated with Fudan University
RECRUITINGShanghai, China
Contact Phone: •••-•••-••••
-
The Second Affiliated Hospital of Air Force Medical University
NOT_YET_RECRUITINGXi'an, China
-
Zhongnan Hospital of Wuhan University
RECRUITINGWuhan, China
Contact Phone: •••-•••-••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can an old alcohol-dependence drug help the immune system fight brain cancer?
- New drug cocktail aims to outsmart childhood brain tumors
- Blood test could spare brain tumor patients from repeated surgeries
- Could HIV drugs help fight brain cancer? new trial launches
- Targeted radiation shows promise for deadly brain tumors
- Promising drug combo targets aggressive brain cancers in youth