HEREDITARY SPASTIC PARAPLEGIA
Clinical trials for HEREDITARY SPASTIC PARAPLEGIA explained in plain language.
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Shocking muscles back to life: new exercise hope for ALS and SMA patients
Symptom relief Recruiting nowThis study tests a special exercise method using whole-body electrical muscle stimulation (WB-EMS) in adults with neuromuscular diseases like ALS, SMA, and muscular dystrophy. Because these conditions make normal exercise hard, WB-EMS directly triggers muscle contractions without…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Spinal zaps could help people with rare paralysis walk better
Symptom relief Recruiting nowThis study tests a noninvasive spinal cord stimulation (tSCS) to improve walking and reduce stiffness in 15 adults with hereditary spastic paraplegia (HSP), a rare nerve condition. Participants receive stimulation through skin electrodes on the lower back twice a week for 8 weeks…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase: NA • Sponsor: Rahul Sachdeva • Aim: Symptom relief
Last updated Apr 30, 2026 15:50 UTC
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New registry aims to unlock secrets of rare paralysis disorder
Knowledge-focused Recruiting nowThis study is creating a detailed registry of 500 people with hereditary spastic paraplegia (HSP), a rare disease that causes progressive leg stiffness and weakness. Researchers will collect medical history, genetic data, and patient feedback over time to better understand how th…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: IRCCS Fondazione Stella Maris • Aim: Knowledge-focused
Last updated May 17, 2026 02:43 UTC
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Researchers launch major effort to map rare nerve disease
Knowledge-focused Recruiting nowThis study is collecting health information and blood samples from 100 people with two types of hereditary spastic paraplegia (SPG4 and SPG5A). The goal is to create a shared database and biobank to help researchers better understand the disease and prepare for future clinical tr…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Gene hunt for rare paralysis disorder launches
Knowledge-focused Recruiting nowThis study aims to uncover the genetic causes of hereditary spastic paraplegia (HSP), a group of rare nerve diseases that cause progressive muscle stiffness and disability. Researchers will analyze DNA from 200 children and adults with HSP to find gene variants linked to the cond…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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New study aims to unlock the secrets of rare genetic movement disorder
Knowledge-focused Recruiting nowThis study collects health information and biological samples from up to 700 people under 30 with early-onset hereditary spastic paraplegia (HSP). Researchers hope to better understand how the disease progresses over time. The goal is to create a registry and biorepository to sup…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC