HEREDITARY SPASTIC PARAPLEGIA
Clinical trials for HEREDITARY SPASTIC PARAPLEGIA explained in plain language.
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Spinal zaps may help stiff legs move freely in rare nerve disease
Symptom relief Recruiting nowThis study tests a noninvasive spinal cord stimulation (tSCS) to improve walking and reduce muscle stiffness in 15 adults with hereditary spastic paraplegia (HSP), a rare nerve condition. Participants receive stimulation through skin electrodes on the lower back twice a week for …
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase: NA • Sponsor: Rahul Sachdeva • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Shocking muscles to move: new exercise hope for nerve disease patients
Symptom relief Recruiting nowThis study tests whether whole-body electrical muscle stimulation (WB-EMS) can help adults with neuromuscular diseases like ALS, SMA, and muscular dystrophy exercise safely. Because these conditions weaken the nerves that control muscles, traditional exercise is often too hard. W…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Scientists probe tiny muscle changes to help kids with cerebral palsy
Knowledge-focused Recruiting nowThis study looks at how muscles grow and change in children with cerebral palsy (CP) by examining tiny samples from leg muscles. Researchers will compare these microscopic findings with muscle images and movement tests. The goal is to better understand why muscles in CP develop d…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New registry aims to unlock secrets of rare neurological disease
Knowledge-focused Recruiting nowThis study is creating a detailed registry of 500 people with hereditary spastic paraplegia (HSP), a rare disorder that causes progressive leg stiffness and weakness. Researchers will collect medical history, genetic data, and patient feedback over time to better understand how t…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: IRCCS Fondazione Stella Maris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Scientists hunt for genetic clues to rare paralysis disorder
Knowledge-focused Recruiting nowThis study aims to uncover the genetic causes of hereditary spastic paraplegia (HSP), a group of rare neurological diseases that cause progressive muscle stiffness and weakness. Researchers at Boston Children's Hospital will analyze DNA from 200 people with HSP to find genetic va…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Researchers launch study to understand rare paralysis conditions
Knowledge-focused Recruiting nowThis study is collecting health data and blood samples from 100 people with specific types of hereditary spastic paraplegia (SPG4 and SPG5A). The goal is to create a shared database and biobank to better understand how the disease progresses. This information will help prepare fo…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Scientists launch major effort to track rare nerve disease in children
Knowledge-focused Recruiting nowThis study collects health information and biological samples from up to 700 people under 30 with early-onset hereditary spastic paraplegia (HSP). Researchers aim to better understand how the disease progresses over time and create a registry for future studies. Participants prov…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC