HEMATOLOGICAL MALIGNANCIES
Clinical trials for HEMATOLOGICAL MALIGNANCIES explained in plain language.
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In-body CAR-T shot aims to revolutionize blood cancer treatment
Disease control Not yet recruitingThis early-phase study tests a new approach to CAR-T therapy for B-cell blood cancers like lymphoma and leukemia. Instead of removing and modifying cells in a lab, the treatment delivers mRNA wrapped in fat particles directly into the body to reprogram immune cells. The goal is t…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: The 923rd Hospital of Joint Logistics Support Force of People's Liberation Army • Aim: Disease control
Last updated Jun 17, 2026 01:30 UTC
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New hope for blood cancer patients with failing transplants
Disease control Not yet recruitingThis study compares luspatercept to epoetin for people with blood cancers who have poor red blood cell production after a stem cell transplant. About 90 adults aged 18-65 will be randomly assigned to receive one of the two drugs. The goal is to see which drug better reduces the n…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2, PHASE3 • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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New drug combo may fix dangerous transfusion problem in blood cancer patients
Disease control Not yet recruitingThis study tests whether a drug called acalabrutinib, alone or with bortezomib, can reduce harmful antibodies that make platelet transfusions ineffective in people with blood cancers. About 42 adults aged 18-65 who have this transfusion problem will be enrolled. The goal is to im…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE3 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC
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New stem cell transplant could help more blood cancer patients find a donor
Disease control Not yet recruitingThis study tests a new way to do stem cell transplants for adults with high-risk blood cancers who don't have a fully matched donor. Doctors will use stem cells from a half-matched (haploidentical) donor and remove certain immune cells to try to prevent severe graft-versus-host d…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: NA • Sponsor: Miltenyi Biomedicine GmbH • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Engineered immune cells aim to stop T-Cell cancers in their tracks
Disease control Not yet recruitingThis study tests a new treatment for people with aggressive T-cell blood cancers, like certain leukemias and lymphomas. It uses specially engineered natural killer (NK) cells from donated cord blood, designed to target and destroy cancer cells. Participants will receive chemother…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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New mRNA shot takes aim at incurable blood cancers
Disease control Not yet recruitingThis early-phase study tests a new drug called WGb-0302 for people with blood cancers like multiple myeloma that have come back or stopped responding to other treatments. The drug uses mRNA technology (similar to some COVID-19 vaccines) to help the body attack cancer cells. The m…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: Sichuan University • Aim: Disease control
Last updated Jun 01, 2026 17:53 UTC
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New drug aims to stop post-transplant anemia in high-risk blood cancer patients
Disease control Not yet recruitingThis study tests whether the drug luspatercept can prevent severe anemia (low red blood cells) after a stem cell transplant in people with blood cancers who also have moderate to severe myelofibrosis (scarring in the bone marrow). About 196 adults aged 18-65 will be randomly assi…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2, PHASE3 • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated May 26, 2026 12:02 UTC
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French study to probe alternative medicine use in blood cancer patients
Knowledge-focused Not yet recruitingThis study looks at how people with blood cancers (like leukemia, lymphoma, or myeloma) in France use complementary and alternative medicines (CAM), such as acupuncture or herbal remedies. Researchers will survey 85 patients and interview some to understand why they use these the…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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AI to predict heart damage from cancer treatments in major european study
Knowledge-focused Not yet recruitingThis study will collect data from up to 10,000 cancer patients across Europe to create better tools for predicting heart damage caused by certain cancer treatments. Researchers will use artificial intelligence alongside standard methods to develop risk scores that doctors can use…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC