HEMATOLOGICAL MALIGNANCIES
Clinical trials for HEMATOLOGICAL MALIGNANCIES explained in plain language.
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New hope for hard-to-treat blood cancers: experimental combo shows promise
Disease control CompletedThis study tested a new drug combination (MK-7684A) in 192 people with blood cancers like lymphoma and multiple myeloma that had returned or stopped responding to other treatments. The goal was to see if the drug is safe and can shrink tumors. While not a cure, it aims to control…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 17, 2026 01:41 UTC
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New drug combo after transplant shows promise for blood cancer patients
Disease control CompletedThis study tested whether giving the drug cyclophosphamide after a stem cell transplant could help the new cells grow better and reduce serious side effects like graft-versus-host disease (GVHD). It included 78 people with blood cancers who received a transplant from a related or…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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Supercharged cord blood transplant shows promise in blood cancer battle
Disease control CompletedThis study tested a new type of cord blood transplant called NiCord, which is grown in a lab to have more stem cells, against standard cord blood transplants for people with blood cancers like leukemia and lymphoma. The goal was to see if NiCord helps the body rebuild its blood a…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE3 • Sponsor: Gamida Cell ltd • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant using a drug called cyclophosphamide to lower the risk of graft-versus-host disease (GVHD) in people with high-risk blood cancers like leukemia and lymphoma. 47 patients received a transplant from a matched sibling donor. The goal…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 08, 2026 13:05 UTC
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PET scans tested as guide for treating hidden fungal infections
Knowledge-focused CompletedThis study looked at whether a special type of PET scan can help doctors decide the best treatment for a rare fungal infection in the liver and spleen. It involved 100 adults with blood cancer or those who had a stem cell transplant. The goal was to see if the scan could track ho…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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Gene type may affect how cancer drug works in patients
Knowledge-focused CompletedThis study looked at how the cancer drug belinostat is processed in the body by people with advanced solid tumors or blood cancers. Researchers wanted to see if a person's genetic makeup (specifically the UGT1A1 gene) changes how the drug works or causes side effects. The study i…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE1 • Sponsor: Acrotech Biopharma Inc. • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:08 UTC