PET scans may guide treatment of hidden fungal infection in cancer patients

NCT ID NCT01916057

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether a special type of PET scan can help doctors diagnose and treat a rare fungal infection of the liver and spleen in people with blood cancer or those who had a stem cell transplant. The infection often appears after severe neutropenia (low white blood cells). The study enrolled 100 adults and compared PET scan results with other tests over time. The goal was to see if the scan could guide treatment decisions, not to test a new drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-FDG PET scan

What this could lead to

If successful, this could show that PET scans are a useful tool for managing treatment of hepatosplenic candidiasis in vulnerable patients.

What could go wrong

This is a small pilot study, not a large trial. It is designed to gather information, not to prove a new treatment works. The results may not change standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disseminated candidiasis hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm immune reconstitution inflammatory syndrome inherited disease susceptibility Invasive Fungal Infections neutropenia systemic mycosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service des Maladies Infectieuses et Tropicales - Centre d'Infectiologie Necker-Pasteur, IHU Imagine - Hôpital Necker-Enfants Malades,

    Paris, 75015, France